不同剂量左氧氟沙星治疗淋病合并非淋菌性尿道炎的临床效果

发布时间：2019-01-12 06:43

【摘要】：目的:对淋病合并非淋菌性尿道炎患者给予不同剂量左氧氟沙星实施治疗的效果进行分析探究。方法:选取在我院接受治疗的80例淋病合并非淋菌性尿道炎患者作为本次研究对象,根据随机数字表法将其平均分为大剂量组与小剂量组两组,分别给予0.5g/次、0.1g/次左氧氟沙星治疗,对比分析两组临床疗效、治疗后2周淋球菌筛查结果以及并发症情况。结果:两组患者均未见不良反应,大剂量组总有效率为95.00%,小剂量组为62.50%,两组相比试验组明显较高,差异有统计学意义(χ~2=15.7404,P=0.00038)。大剂量组研究对象的淋球菌检测阳性率(2.50%)与小剂量组淋球菌检测阳性率(35.00%)相比明显较低,差异有统计学意义(χ~2=13.8667,P=0.0002)。大剂量组研究对象的并发症发生率(5.00%)与对照组(37.50%)相比明显较低,差异有统计学意义(χ~2=10.7563,P=0.00104)。结论:对淋病伴非淋菌性尿道炎患者采用大剂量左氧氟沙星治疗的效果显著,复查结果较好,药物抗菌性较强,并发症较少发生,具有较高的安全性,值得推广。
[Abstract]:Objective: to investigate the effect of levofloxacin on gonorrhea complicated with nongonococcal urethritis. Methods: 80 cases of gonorrhea complicated with nongonococcal urethritis were selected as the study object. According to the method of random digital table, they were divided into two groups: high dose group and small dose group. 0.1g/ sublevofloxacin treatment, the two groups of clinical efficacy, 2 weeks after treatment results of gonococcal screening and complications. Results: there were no adverse reactions in the two groups. The total effective rate was 95.00 in the high dose group and 62.50 in the low dose group. The difference between the two groups was statistically significant (蠂 ~ 2 = 15.7404, P < 0.00038). The positive rate of Neisseria gonorrhoeae in the high-dose group (2.50%) was significantly lower than that in the low-dose group (35.00%) (蠂 ~ 213.8667P0.0002). The incidence of complications in the high-dose group (5.00%) was significantly lower than that in the control group (37.50%) (蠂 ~ (2) 10.7563P ~ (0.00104). Conclusion: high dose levofloxacin is effective in the treatment of gonorrhea with nongonococcal urethritis.
【作者单位】：恩施市中心医院皮肤科;
【分类号】：R759.2;R695

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