四川口岸首例输入性三日疟病例分析
发布时间：2019-02-12 06:51
【摘要】：目的分析四川口岸首例输入性三日疟感染病例的临床表现及实验室检测结果,为四川地区三日疟的预防控制提供参考依据。方法对2017年四川口岸1例疟疾患者采集血样,采用BinaxNow疟疾快速诊断试剂盒、瑞吉染色镜检和实时荧光PCR方法进行鉴定。结果疟疾快速诊断试剂盒检测患者血样为除恶性疟原虫以外的间日疟原虫、三日疟原虫或卵形疟原虫感染;血涂片镜检为三日疟原虫,密度为2 400/μl;实时荧光PCR检测三日疟原虫核酸阳性。结论结合血涂片、PCR等检测结果、流行病学资料和临床表现,该患者确诊为输入性三日疟原虫感染病例。提示应加强疟防专业人员三日疟诊治技能培训,以减少误诊误治。
[Abstract]:Objective to analyze the clinical manifestations and laboratory results of the first imported 3-day malaria infection in Sichuan Port, and to provide a reference for the prevention and control of 3-day malaria in Sichuan. Methods Blood samples were collected from a case of malaria in Sichuan Port in 2017. The rapid diagnosis kit of BinaxNow malaria was used to identify the patients with malaria by Ruigi staining microscopy and real-time fluorescence PCR. Results the blood samples of the patients were vivax except Plasmodium falciparum, Plasmodium vivax or Plasmodium ovum infection with rapid diagnostic kit, and the blood smear showed Plasmodium falciparum with a density of 2 400 / 渭 l. Real-time fluorescence PCR was used to detect nucleic acid of Plasmodium falciparum. Conclusion combined with the results of blood smear, PCR, epidemiological data and clinical manifestations, the patient was diagnosed as imported infection of Plasmodium falciparum. The results suggest that the training of 3-day malaria diagnosis and treatment skills should be strengthened for malaria control professionals in order to reduce misdiagnosis and mistreatment.
【作者单位】： 四川国际旅行卫生保健中心;中国疾病预防控制中心寄生虫病预防控制所卫生部寄生虫病原与媒介生物学重点实验室世界卫生组织热带病合作中心科技部热带病国际合作中心;
【基金】：国家质检总局科研基金项目(No.2016IK244) 四川省科技基金项目(No.2017RZ0053)
【分类号】：R531.3
本文编号：2420165
[Abstract]:Objective to analyze the clinical manifestations and laboratory results of the first imported 3-day malaria infection in Sichuan Port, and to provide a reference for the prevention and control of 3-day malaria in Sichuan. Methods Blood samples were collected from a case of malaria in Sichuan Port in 2017. The rapid diagnosis kit of BinaxNow malaria was used to identify the patients with malaria by Ruigi staining microscopy and real-time fluorescence PCR. Results the blood samples of the patients were vivax except Plasmodium falciparum, Plasmodium vivax or Plasmodium ovum infection with rapid diagnostic kit, and the blood smear showed Plasmodium falciparum with a density of 2 400 / 渭 l. Real-time fluorescence PCR was used to detect nucleic acid of Plasmodium falciparum. Conclusion combined with the results of blood smear, PCR, epidemiological data and clinical manifestations, the patient was diagnosed as imported infection of Plasmodium falciparum. The results suggest that the training of 3-day malaria diagnosis and treatment skills should be strengthened for malaria control professionals in order to reduce misdiagnosis and mistreatment.
【作者单位】： 四川国际旅行卫生保健中心;中国疾病预防控制中心寄生虫病预防控制所卫生部寄生虫病原与媒介生物学重点实验室世界卫生组织热带病合作中心科技部热带病国际合作中心;
【基金】：国家质检总局科研基金项目(No.2016IK244) 四川省科技基金项目(No.2017RZ0053)
【分类号】：R531.3
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