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泛耐药鲍氏不动杆菌医院感染患者临床特点及预后分析

发布时间:2019-04-17 17:43
【摘要】:目的总结泛耐药鲍氏不动杆菌(PDRAB)医院感染患者的临床特点,分析其感染患者的预后危险因素,为临床治疗提供合理依据。方法回顾性总结2010年1月-2012年12月176例PDRAB医院感染患者临床资料,根据其预后分为存活组110例和死亡组66例,采用单因素分析及logistic逐步回归法对感染患者的危险因素进行分析。结果 176例PDRAB医院感染患者死亡66例,病死率为37.5%;多发生于中心ICU占60.8%,其次为烧伤病区占22.7%;主要为下呼吸道感染占80.7%,其次为创面分泌物占10.9%,血液、静脉导管、泌尿道感染分别占4.5%、2.8%、1.1%;存活组与死亡组比较,年龄、基础疾病、机械通气、恶性肿瘤、总住院时间、ICU治疗时间和APACHEⅡ评分等7个危险因素,差异均有统计学意义(P0.05);多因素logistic回归分析后发现APACHEⅡ评分(P=0.000,OR值1.414,95%CI 1.262~1.585)是死亡的独立危险因素(P0.01)。结论 PDRAB医院感染患者病死率较高,高龄、基础疾病多、ICU住院时间长等多种危险因素对患者的预后产生不良影响,APACHEⅡ评分是PDRAB感染患者预后危险因素的重要评估指标。
[Abstract]:Objective to summarize the clinical characteristics and prognostic risk factors of patients with nosocomial infection of pan-drug resistant Acinetobacter baumannii (PDRAB), so as to provide a reasonable basis for clinical treatment. Methods the clinical data of 176 patients with PDRAB nosocomial infection from January 2010 to December 2012 were retrospectively reviewed. According to their prognosis, they were divided into survival group (110 cases) and death group (66 cases). Univariate analysis and logistic stepwise regression were used to analyze the risk factors of infected patients. Results 66 cases died of PDRAB nosocomial infection, the mortality rate was 37.5%, most of them occurred in the center of ICU (60.8%), followed by burn area (22.7%), the mortality rate was 37.5%, and the mortality rate was 37.5%. The main causes were lower respiratory tract infection (80.7%), wound secretion (10.9%), blood infection (4.5%), venous catheter (2.8%) and urinary tract infection (1.1%). There were significant differences in age, basic disease, mechanical ventilation, malignant tumor, total hospital stay, ICU treatment time and Apache 鈪,

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