各型肝包虫囊肿的生物、物理、化学性状改变的实验研究

发布时间：2019-05-10 06:37

【摘要】：目的：观察不同分型的囊型肝包虫生物学、物理学、化学性状变化，探讨该变化是否遵循一定规律，，为肝包虫自然病程的研究提供参考。 方法：收集2012年10月1日至2013年12月31日所有肝包虫病人资料及包虫标本50例，对不同类型的肝包虫囊肿进行HE染色、玻璃管法测定囊内压，冰点法测定囊液渗透压，酸度计法测定囊内容物PH值，原子吸收法测量不同类型肝包虫囊肿囊内容物中钙的含量。 结果：各型包虫囊肿囊液PH值均为碱性，其中I型包虫囊肿囊液的PH值与人体PH值相同，从I型向Ⅳ型发展，其囊液PH值呈逐渐降低趋势，Ⅰ型包虫囊肿囊内压力最高，Ⅳ型包虫囊肿囊内压力最低，从Ⅰ型至Ⅳ型包虫囊肿其囊内压力逐渐下降，从Ⅰ至Ⅲ型包虫囊肿，其囊液渗透压逐渐增高，从Ⅰ型至Ⅴ型包虫囊肿其囊内容物钙离子含量逐渐增高，单囊型（Ⅰ型）和多子囊型（Ⅱ型）的肝包虫囊肿内囊分为内外两层，内层为生发层，可见有生殖细胞的头节和生发囊；外层为多层的角质层，白色半透明，并且有弹性。随着分型的不同，在多数塌陷型（Ⅲ型）和实变型（Ⅳ型）、钙化型（Ⅴ型）包虫囊肿，其内囊生发层细胞逐渐脱落,角质层板层分离,厚薄不等,结构断裂,着色度差且变薄。 结论：不同囊型肝包虫的影像学表现不同，其物理、化学、生物学性状亦不相同，随着包虫囊肿从Ⅰ型到Ⅴ型的变化，其囊内环境呈有规律的变化，即囊液的PH值、囊内压力呈逐渐下降趋势，囊液渗透压及钙离子含量呈逐渐升高趋势，内囊的完整性逐渐遭到破坏。
[Abstract]:Objective: to observe the changes of biological, physical and chemical characters of different types of cysticercosis, and to explore whether the changes follow certain rules, so as to provide reference for the study of the natural course of hepatic echinococcosis. Methods: from October 1, 2012 to December 31, 2013, all the data of hepatic hydatid cyst and 50 cases of hydatid cyst were collected. The different types of hepatic hydatid cyst were stained with HE, the intracapsule pressure was measured by glass tube method, and the osmotic pressure of cyst fluid was measured by freezing point method. Ph value was measured by acidity meter and calcium content in cyst contents of different types of hepatic hydatid cyst was measured by atomic absorption spectrometry (AAS). Results: the PH values of all types of hydatid cyst fluid were alkaline. The PH value of type I hydatid cyst fluid was the same as that of human body. From type I to type IV, the PH value of cyst fluid decreased gradually, and the pressure in the cyst of type I hydatid cyst was the highest. The pressure in the cyst of type IV hydatid cyst was the lowest, the pressure in cyst fluid decreased gradually from type 鈪

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