2009-2015年河北省流感病原学监测结果分析

发布时间：2019-05-28 22:35

【摘要】：目的了解河北省2009-2015年流感病原学特征,为流感防控提供科学依据。方法采用描述性流行病学方法对2009年4月1日-2015年3月31日的流感病原学监测资料进行分析。结果采集的63 397份流感样病例(Influenza-like Illness,ILI)标本经流感病毒核酸检测,10 705份阳性(阳性率为16.89%),其中甲型H1N1亚型4 179份,季节性H3亚型3 674份,B型2 595份,A型未分型230份,季节性H1亚型10份,混合型15份。传代狗肾细胞分离到流感毒株2 865株。6个监测年度流感病毒核酸阳性率分别为29.18%、12.58%、12.97%、13.34%、11.64%和15.95%,2009-2010年度流感病毒核酸检测阳性率显著高于其余5个监测年度(χ2=1997.585,P0.01);6个监测年度,流感流行的高峰期分别为11月、1月、2月、1月、1月、12月,优势病毒分别为甲型H1N1流感、甲型H1N1+季节性H3流感、B型流感、季节性H3+甲型H1N1流感、甲型H1N1流感、季节性H3流感;2013年之前,B-Victoria系为主要流行型别,自2012年B-Yamagata系出现后取代B-Victoria系成为主要的流行株;0~、5~、15~、25~和≥60岁年龄组的阳性率分别为12.12%、24.88%、18.25%、15.99%和13.78%,阳性率差异有统计学意义(χ2=880.864,P0.01),5~岁年龄组阳性率最高。结论 2009-2015年河北省以甲型H1N1流感病毒流行为主;随年度甲型H1N1、季节性H3、B型流感病毒呈共同或先后交替流行的特点;高峰期出现在当年11月~次年2月,5~年龄组为易感人群。
[Abstract]:Objective to understand the etiological characteristics of influenza in Hebei Province from 2009 to 2015, and to provide scientific basis for influenza prevention and control. Methods descriptive epidemiological method was used to analyze the etiological surveillance data of influenza from April 1, 2009 to March 31, 2015. Results 63 397 influenza like cases (Influenza-like Illness,ILI) were detected by influenza virus nucleic acid, and 10 705 samples were positive (the positive rate was 16.89%). Among them, 4 179 were type A H1N1, 3 674 were seasonal H3, 2 595 were type B, 4 179 were influenza A subtypes, 3 674 were seasonal H3 subtypes, 2 595 were influenza B, 10 705 were positive (positive rate was 16.89%). There were 230 unclassified type A, 10 seasonal H 1 subtypes and 15 mixed types. 2865 strains of influenza virus were isolated from subculture dog kidney cells. The positive rates of nucleic acid of influenza virus in six monitoring years were 29.18%, 12.58%, 12.97%, 13.34%, 11.64% and 15.95%, respectively. The positive rate of influenza virus nucleic acid detection in 2009 / 2010 was significantly higher than that in the other five monitoring years (蠂 ~ 2 鈮，

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