日粮添加β-葡聚糖对仔猪生长性能、肠道发育与免疫功能的影响

发布时间：2018-01-30 12:06

本文关键词： β-葡聚糖断奶仔猪生长性能免疫功能肠道发育　出处：《中国兽医学报》2017年11期 　论文类型：期刊论文

【摘要】：选取30头28日龄健康断奶仔猪(杜长大),随机分为3组,每组10个重复,每个重复1头猪。对照组饲喂基础日粮,试验1组在基础日粮中添加100mg/kg硫酸黏杆菌素,试验2组在基础日粮中添加400mg/kgβ-葡聚糖,试验期为28d。结果表明:与对照组和抗生素组相比,日粮添加400mg/kgβ-葡聚糖显著提高断奶仔猪的末重,平均日增重,平均日采食量,肉料比,脾脏指数,血浆T-AOC、T-SOD、CAT、NOS、GR、GSH-Px浓度,回肠绒毛高度,空肠黏膜TLR4、β-defensins-2蛋白浓度(P0.05);降低血浆ALT和AST浓度,空肠、回肠和结肠的隐窝深度,空肠黏膜HSP90和PAPR-1蛋白浓度,IL-8和TGF-β1mRNA水平(P0.05)。结论:在日粮中添加400 mg/kgβ-葡聚糖可替代100mg/kg饲料添加型抗生素硫酸粘杆菌素,从而提高断奶仔猪的生产性能、提高动物血液的抗氧化能力、增强断奶仔猪机体免疫力。
[Abstract]:Thirty 28 day-old healthy weaned piglets were randomly divided into 3 groups, 10 replicates in each group and 1 in each. The control group was fed with basic diet. In group 1, 100 mg / kg mucin sulfate was added to the basal diet, and 400 mg / kg 尾 -glucan was added to the basal diet in group 2. The experiment period was 28 days. The results showed that the supplementation of 400 mg / kg 尾 -glucan significantly increased the litter weight, average daily gain and average daily intake of weaned piglets compared with the control group and antibiotic group. Ratio of meat to feed, spleen index, plasma T-AOCU T-SOD, GSH-Px concentration, ileal villi height, jejunal mucosal TLR4. 尾 -defensins-2 protein concentration: P0.05; The levels of plasma ALT and AST, the depth of recess in jejunum, ileum and colon, and the concentration of HSP90 and PAPR-1 protein in jejunum mucosa were decreased. IL-8 and TGF- 尾 1 mRNA levels (P0.05). Conclusion: the addition of 400 mg/kg 尾-glucan in diet can replace 100 mg / kg of antibiotic myxobistin sulfate. In order to improve the performance of weaning piglets, improve the antioxidant capacity of animal blood, enhance the body immunity of weaning piglets.
【作者单位】：西南大学生物饲料与分子营养实验室;
【基金】：国家“937”计划资助项目(2013CB127303) 国家“948”项目(2015Z74) 西南大学基本科研业务费(XDJK2014B028,XDJK2015D006,XDJK2016D010)
【分类号】：S828.5
【正文快照】： *Corresponding author,E-mail:tangzhiru2326@sina.com仔猪的消化器官成熟较晚,消化酶系统发育较差,胃底腺分泌的胃酸减少,仔猪肠道蠕动能力减弱,消化功能降低[1]。仔猪断奶后,肠道内乳酸杆菌等有益菌数量减少,大肠杆菌、沙门菌等有害菌数量增加,肠道菌群失衡[2],使断奶仔猪

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