脂肪发育相关lncRNA的研究进展

发布时间：2018-03-14 23:15

本文选题：lncRNA　切入点：脂肪生成　出处：《中国畜牧杂志》2017年10期 　论文类型：期刊论文

【摘要】：提高肉品质已成为当前家畜遗传育种的重要目标。肌内脂肪含量与肉的嫩度、大理石花纹和风味密切相关。脂肪的过度沉积不仅影响肉品质,而且与人类的各种疾病密切相关。脂肪的生成非常复杂,受多种转录调控因子、作用通路以及调控网络的共同作用。长链非编码RNA(lncRNA)是新发现的一类参与大量重要生物学功能的长度大于200个核苷酸的RNA分子,在调控脂肪发育过程中扮演着重要角色。本文主要就lncRNA特点、功能及国内外报道的与脂肪发育相关lncRNA的研究进展进行综述,以期为动物脂肪发育的调控机制研究提供参考。
[Abstract]:Improving meat quality has become an important goal in animal genetics and breeding. Intramuscular fat content is closely related to meat tenderness, marbling and flavor. Excessive fat deposition not only affects meat quality, but also improves meat quality. And it's closely related to all kinds of diseases in humans. Fat production is very complex and is regulated by a variety of transcriptional regulators. Long chain noncoding RNAs (LNRNAs) are a newly discovered class of RNA molecules with a length of more than 200 nucleotides involved in a large number of important biological functions. This article reviews the characteristics and functions of lncRNA and the research progress of lncRNA related to adipose development reported at home and abroad in order to provide reference for the study of the regulation mechanism of animal adipose development.
【作者单位】：宁夏大学农学院;宁夏畜牧工作站;
【分类号】：S852.2

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