犬超声心动参数及地西泮镇静后的变化

发布时间：2018-03-19 03:04

本文选题：犬　切入点：超声心动图　出处：《南京农业大学学报》2017年02期 　论文类型：期刊论文

【摘要】：[目的]本文旨在研究犬超声心动参数及地西泮镇静后的变化规律。[方法]在二维超声图像引导下,用M模式记录并测量33只健康成年犬右侧胸骨旁心脏长轴四腔观和左心室流出道的左心室舒张末期直径(LVEDD)、收缩末期直径(ESD)、舒张期室间隔厚度(IVSD)、左心室壁舒张期厚度(LVWD)、二尖瓣前叶E峰与室间隔分开的距离(EPSS)、主动脉根直径(Ao)和左心房舒张末期直径(LA),供试犬按体质量分为4组,计算各参数与体质量间的相关性;在此基础上以6只健康成年犬为研究对象,用地西泮镇静后0、5、10、15、20、25、30、35和40 min分别实时记录各参数的变化。[结果]在M模式下各测量值随犬体质量增加而增加,M型超声心动参数的大小与体质量呈明显正相关,两者线性回归关系表现为极显著(P0.001);用地西泮镇静15 min后左心室EDD平均值显著下降(P0.05),用药40 min后平均值极显著下降(P0.01);各组供试犬左心室LVWD及IVSD平均值差异不显著(P0.05);用药30 min后ESD显著下降;用药20、25及40 min后的EPSS显著下降(P0.05);用药40 min后Ao显著下降(P0.05);用药20及40 min后的LA显著下降(P0.05)。[结论]表明地西泮对犬超声心动图的影响主要表现为缩小左心室舒张末期的直径。
[Abstract]:[objective] to study the parameters of canine echocardiography and the changes of diazepam after sedation. [methods] under the guidance of two-dimensional ultrasound image, M mode was used to record and measure left ventricular end-diastolic diameter (LVEDDD), end-systolic diameter (ESD), diastolic septal thickness (IVSD), left ventricular wall diastolic thickness (LVMD), left ventricular end-diastolic diameter (LVEDDD) and left ventricular wall diastolic thickness (LVEDDD) in 33 healthy adult dogs with long axis four-chamber view of right parasternal heart and left ventricular outflow. The distance between the E peak of mitral anterior lobe and the ventricular septum (EPSS), aortic root diameter (Aoo) and left atrial end-diastolic diameter (LAA) were measured. The dogs were divided into 4 groups according to their body mass. The correlation between parameters and body mass was calculated, and six healthy adult dogs were studied. After sedation with diazepam, the changes of parameters were recorded in real time at 35 and 40 min, respectively. [results] there was a significant positive correlation between the size of parameters and the body mass of the parameters in M mode. The linear regression relationship between the two groups was extremely significant (P 0.001), the mean value of left ventricular EDD decreased significantly after 15 min of diazepam sedation, and the average value of left ventricular EDD decreased significantly after 40 min administration of diazepam, and there was no significant difference in the mean value of LVWD and IVSD between the three groups (P 0.05). ESD decreased significantly after 30 min treatment. After 20 min and 40 min treatment, EPSS decreased significantly (P 0.05), Ao decreased significantly after 40 min, LA decreased significantly after 20 and 40 min. [conclusion] the effect of diazepam on left ventricular end-diastolic diameter in dogs was mainly manifested as narrowing of left ventricular end-diastolic diameter.
【作者单位】：南京农业大学动物医学院;上海爱侣宠物有限公司;
【基金】：教育部高等学校博士学科点专项科研基金资助项目(20130097110020)
【分类号】：S854.42;S859.7

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