猪塞尼卡谷病毒流行态势与诊断防控研究进展

发布时间：2018-03-26 20:03

本文选题：塞尼卡谷病毒　切入点：猪水泡病　出处：《微生物学通报》2017年12期

【摘要】：塞尼卡谷病毒(Seneca valley virus,SVV)为小RNA病毒科塞尼卡病毒属的唯一成员,2002年首次发现于PER.C6细胞培养物中,被鉴定为细胞培养基中的污染物。最初SVV被用作溶瘤病毒进行肿瘤治疗研究。现已证实SVV感染猪能够引发原发性水泡病,引起猪的鼻吻、蹄部冠状带的水泡病变,同时伴有跛行、厌食、嗜睡和发烧等临床表现。与口蹄疫、猪水泡病和水泡性口炎引起的临床症状难以区分。2015-2017年期间,在美国、中国、泰国等多个国家暴发了SVV疫情,并且流行范围逐步扩大。针对该病的不断扩散,急需提出和制定有效的诊断与防控策略及措施。因此,一些新的诊断方法被不断开发出来,新的防控策略也在逐步建立。本文主要针对SVV最新的流行态势及特点、诊断与防控技术进行综述,旨在提供SVV最新研究进展,提高疾病防控及科研工作人员对该病的进一步认识和了解,为该病的防控提供理论依据和参考。
[Abstract]:Seneca valley virus (SVV) is the only member of the genus Coxenica virus of small RNA virus. It was first found in PER.C6 cell culture in 2002. SVV was identified as a contaminant in cell culture medium. SVV was initially used for tumor therapy of tumorytic virus. It has been shown that SVV infection can cause primary vesicular disease, nasal anastomosis, and blister lesions in the coronal zone of the hoof. With clinical symptoms such as claudication, anorexia, lethargy and fever. It is difficult to distinguish the clinical symptoms caused by foot-and-mouth disease, pig blister disease and blistering stomatitis. During 2015-2017, SVV outbreaks broke out in the United States, China, Thailand and many other countries. In view of the continuous spread of the disease, it is urgent to put forward and formulate effective diagnosis, prevention and control strategies and measures. Therefore, some new diagnostic methods have been continuously developed. A new strategy of prevention and control is also being established. This paper summarizes the latest epidemic situation and characteristics of SVV, diagnosis and prevention and control technology, in order to provide the latest research progress of SVV. To improve the knowledge and understanding of disease prevention and control and scientific research staff to provide theoretical basis and reference for disease prevention and control.
【作者单位】：甘肃农业大学动物医学院;中国农业科学院兰州兽医研究所家畜疫病病原学国家重点实验室口蹄疫国家参考实验室;
【基金】：国家自然科学基金项目(No.U1501213,31672585) 甘肃省杰出青年基金项目(No.1606RJDA313) 甘肃省自然科学基金项目(No.1606RJYA280)~~
【分类号】：S858.28

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