三聚氰胺对肉鸡的亚慢性毒性研究

发布时间：2018-04-08 10:39

本文选题：三聚氰胺　切入点：肉鸡　出处：《中国家禽》2017年11期

【摘要】：试验旨在研究三聚氰胺对肉鸡的亚慢性毒性。选取120只1日龄健康AA肉鸡,随机分成5组,第1组为对照组,第2~5组为试验组,分别饲喂含三聚氰胺0、40、120、360和1 080 mg/kg的饲料,试验期为60 d。结果表明,肉鸡摄入含三聚氰胺360 mg/kg和1 080 mg/kg的饲料,出现明显的中毒症状和死亡,肉鸡料重比、平均日增重极显著低于对照组(P0.01);血浆丙氨酸氨基转氨酶(ALT)和天门冬氨酸氨基转氨酶(AST)活性、血浆肌酐、尿酸含量以及肝脏和肾脏指数显著高于对照组(P0.05)。肉鸡摄入含三聚氰胺40 mg/kg和120 mg/kg的饲料,其生产性能、血液生化指标及脏器指数与对照组无明显差异(P0.05)。由此可见,肉鸡摄入饲料中三聚氰胺含量高于360 mg/kg可发生三聚氰胺中毒,中毒靶器官是肝脏和肾脏;饲料中三聚氰胺对肉鸡的无可见有害作用水平为120 mg/kg。
[Abstract]:The aim of this study was to study the subchronic toxicity of melamine to broilers.120 1-day-old healthy AA broilers were randomly divided into 5 groups, the first group was the control group and the second group was the experimental group. The diets containing melamine 040120360 and 1080 mg/kg were fed respectively for 60 days.The results showed that the diet containing melamine 360 mg/kg and 1 080 mg/kg had obvious toxic symptoms and death, and the feed weight ratio of broiler chickens.Average daily gain (ADG) was significantly lower than that of control group (P 0.01), plasma alanine aminotransferase (alt) and aspartate aminotransferase (AST) activity, plasma creatinine, uric acid content and liver and kidney index were significantly higher than those in control group (P 0.05).There was no significant difference in production performance, blood biochemical index and viscera index between broiler and control group when fed with 40 mg/kg and 120 mg/kg melamine.It can be seen that melamine poisoning can occur in broilers when the content of melamine in feed is more than 360 mg/kg, and the toxic target organs are liver and kidney, and the level of no visible harmful effect of melamine on broilers is 120 mg / kg.
【作者单位】：临沂大学农林科学学院;青岛农业大学动物科技学院;
【基金】：基金项目:山东省现代农业产业技术体系家禽产业创新团队(SDAIT-11-07、SDAIT-11-17)
【分类号】：S858.31

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