马腺疫、马急腹症的临床病案分析

发布时间：2018-06-09 02:43

本文选题：马 + 急腹症　；参考：《新疆农业大学》2015年硕士论文

【摘要】：随着马匹的日益增加,马腺疫等传染病严重的影响着马匹生长发育,马急腹症等内科病对国外引进的优质马匹造成了生命威胁,因此,本研究通过分析2013年3月至2015年3月新疆伊犁昭苏县某马场的临床病案,制定一个有效的治疗方案对今后发生马腺疫及马急腹症防治提供临床依据。通过临床症状诊断分析、直肠检查、实验室血液学分析和治疗马的急腹症病例34例、马腺疫76例。马急腹症应用中药、西药及中西结合治疗,其中31例马急腹症痊愈,3例肠因扭转病治疗无效死亡,治愈率达91.2%;马腺疫发病率为49%,其中幼驹98.6%,成年马1.4%,应用中药、西药及中西医结合治疗,一过型病畜35例,典性型27例,恶性型14例,继发脓毒败血症死亡4例,治愈率为94.7%,病死率为5.3%。血液学检测结果显示:(1)采用西药治疗马腺疫后,白细胞和红细胞的数量以及红细胞压积还有淋巴细胞数以及血红蛋白指标的变化恢复到正常范围内(P0.01);生化测定显示白蛋白升高(P0.01)和天冬氨酸氨基转移酶升高(P0.05);检测马血清中的TNF-α和IL-6含量均降低,但是变化不明显(P0.05)。中药透脓散治疗马腺疫后,白细胞数、血红蛋白含量降低至正常(P0.05),而且用药后的红细胞数升高而粒细胞数降低这两项的均值有较为明显的变化(P0.01),平均血红蛋白浓度和红细胞压积这两项均值用药后有所升高;血糖升高(P0.01)、白蛋白显着升高至正常范围内(P0.05)、而甘油三脂和直接胆红素以及天门冬氨酸氨基转移酶以及碱性磷酸酶降低(P0.05);TNF-α的均值降低(P0.01)而血清中IL-6的均值降低但无显著差异。(2)西药治疗急腹症红细胞压积明显的下降、西药和中西结合治疗血红蛋白浓度升高至正常值(P0.05);总蛋白(TP)下降(P0.05)以及钠离子(Na+)均值变化显著下降(P0.01);TNF-α和IL-6的均值均有所降低(P0.05)。临床中应用中药治疗马腺疫效果比西药治疗效果好,中西结合治疗马急腹症效果较好,为今后马腺疫及马急腹症的治疗和预防提供参考依据。
[Abstract]:With the increasing number of horses, infectious diseases such as horse adenosis have seriously affected the growth and development of horses. Medical diseases such as acute abdominal diseases of horses have posed a threat to the lives of imported high-quality horses from abroad. This study analyzed the clinical records of a horse farm in Zhaosu County, Xinjiang from March 2013 to March 2015, and established an effective treatment plan to provide clinical basis for the prevention and treatment of horse gland disease and horse acute abdomen in the future. Through clinical symptom diagnosis and analysis, rectal examination, laboratory hematology analysis and treatment of horse acute abdomen cases 34 cases, horse adenosis 76 cases. Chinese medicine, western medicine and Chinese medicine were used in the treatment of horse acute abdomen. Among them, 31 cases of acute abdomen were cured and 3 cases died from torsion disease, and the cure rate reached 91.2%. The incidence rate of horse gland disease was 49, in which the young horse was 98.6 and the adult horse 1.4 was treated with traditional Chinese medicine. There were 35 cases of one-pass disease, 27 cases of classical type, 14 cases of malignant type and 4 cases of secondary sepsis death. The cure rate was 94.7% and the mortality was 5.3%. The results of hematological examination showed that: 1) after using western medicine to treat horse adenosis, The changes of leukocyte and erythrocyte count, hematocrit, lymphocyte number and hemoglobin index returned to normal range (P0.01a); biochemical test showed that albumin increased P0.01) and aspartate aminotransferase (aspartate aminotransferase) increased P0.05a; The levels of TNF- 伪 and IL-6 in horse serum were all decreased. But the change was not obvious (P 0.05). After the treatment of horse gland disease with traditional Chinese medicine, the number of white blood cells, The content of hemoglobin decreased to normal P0.05, and the mean value of RBC increased and granulocyte decreased. The mean hemoglobin concentration and hematocrit increased after treatment. Serum levels of IL-6 decreased but not in serum, while triglyceride and direct bilirubin, aspartate aminotransferase and alkaline phosphatase decreased the mean value of TNF- 伪. Significant difference. 2) the decrease of hematocrit in the treatment of acute abdomen with western medicine, The concentration of hemoglobin increased to the normal value (P0.05), the total protein (TP) decreased (P0.05) and the mean value of sodium ion (Na) decreased significantly (P 0.01) and the mean of TNF- 伪 and IL-6 decreased significantly (P 0.05). The therapeutic effect of traditional Chinese medicine is better than that of western medicine in the treatment of horse gland disease, and the combination of Chinese and western medicine is better in the treatment of horse acute abdomen, which provides a reference for the treatment and prevention of horse gland disease and horse acute abdomen in the future.
【学位授予单位】：新疆农业大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：S858.21

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