10%磷酸替米考星可溶性粉在靶动物鸡的安全性试验

发布时间：2018-06-18 09:13

本文选题：%磷酸替米考星可溶性粉 + 鸡　；参考：《中国畜牧兽医》2017年04期

【摘要】：为评价10%磷酸替米考星可溶性粉对靶动物鸡的安全性,本试验选择40只25日龄健康白羽杂交肉鸡,随机分为4组,每组10只,公母各半。各组分别以0(0mg/L)、1(75mg/L,以替米考星计)、3(225mg/L,以替米考星计)和5(375mg/L,以替米考星计)倍推荐剂量的10%磷酸替米考星可溶性粉混饮给药,连用9d。试验期间观察鸡的临床表现、体重变化和饲料消耗,试验结束后进行病理学检查,并测定血液生理指标和血清相关生化指标的变化。结果显示,10%磷酸替米考星可溶性粉在本试验条件下以5倍以下剂量饮水给药对鸡的生长性能无显著影响(P0.05),在血液生理指标及血清生化指标方面,不具有剂量依赖性的显著变化(P0.05)。该试验结果表明,10%磷酸替米考星可溶性粉按推荐剂量(75mg/L)饮水给药对靶动物鸡具有较大的安全性。
[Abstract]:In order to evaluate the safety of 10% timicosin phosphate soluble powder on target chickens, 40 healthy white feather broilers aged 25 days were randomly divided into 4 groups, 10 in each group, male and female. Each group was given 10% tenmicosin phosphate soluble powder for 9 days with 0 ~ 0 mg / L / L ~ 1 ~ 75 mg 路L ~ (-1), 35 ~ (25 mg / L) and 5 ~ 5 ~ 375 mg / L ~ (-1) of tenmicosine phosphate soluble powder for 9 days, respectively, and 10% timicosin phosphate soluble powder (10%) was used for 9 days, and the dosage of 10% timicosin phosphate soluble powder was used for 9 days, and the dose of 10% timicosine phosphate soluble powder was used for 9 days. The clinical manifestation, weight change and feed consumption of chickens were observed during the experiment. Pathological examination, blood physiological index and serum biochemical index were performed after the experiment. The results showed that 10% timicosin phosphate soluble powder had no significant effect on the growth performance of chicken under the condition of drinking water of less than 5 times, but had no significant change in blood physiological index and serum biochemical index in a dose-dependent manner. The results showed that drinking water administration of 10% timicosin phosphate soluble powder with recommended dosage of 75 mg / L was safe for target chickens.
【作者单位】：扬州大学兽医学院;江苏农牧科技职业学院;齐鲁动物保健品有限公司;江苏省动物重要疫病与人兽共患病防控协同创新中心;
【基金】：“江苏高校优势学科建设工程资助项目”(PAPD) 横向合作项目(NSFPT1405)
【分类号】：S859.7

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