大型集约化商品肉鸡场防疫措施研析
发布时间:2018-07-06 10:52
本文选题:商品肉鸡 + 新城疫 ; 参考:《内蒙古农业大学》2015年硕士论文
【摘要】:近年来我国商品肉鸡业发展迅猛,综合性防疫是保障商品肉鸡健康生长的关键措施,但很多商品肉鸡场缺乏规范的综合性防疫措施,新城疫、禽流感两大主要传染病免疫程序不科学,消毒药物使用不合理,严重影响防疫效果,阻碍肉鸡业的健康发展。为此,本研究紧密结合商品肉鸡生产,实地进行了商品肉鸡新城疫、H9亚型禽流感免疫程序试验研究及空鸡舍不同消毒药物消毒效果比较试验,以期制定出适合试验所在大型商品肉鸡场科学合理的新城疫和H9亚型禽流感免疫程序,筛选出适合空鸡舍的消毒药物,为我国大型商品肉鸡场制定综合性防疫措施提供建议性的技术参考。对采用两个不同的商品肉鸡新城疫免疫程序免疫的鸡群进行了抗体检测,结果表明,商品肉鸡雏鸡2日龄时新城疫母源抗体滴度高达9.1log2,以后呈逐步下降趋势,7日龄以后抗体滴度低于保护临界值(6log2);7日龄采用弱毒疫苗首免、19日龄采用灭活疫苗二免、28日龄采用灭活疫苗三免是适合于试验所在大型商品肉鸡场的较好的新城疫免疫程序,在整个42天的饲养期内抗体滴度基本维持在有效保护水平以上,能够较好的保护鸡群免受新城疫病毒的感染。对采用两个不同的商品肉鸡H9亚型禽流感免疫程序免疫的鸡群进行了抗体检测,结果表明,商品肉鸡雏鸡2日龄时H9亚型禽流感母源抗体滴度高达9.52log2,以后呈逐步下降趋势,11日龄时抗体滴度接近保护临界值(4log2);11-12日龄一次免疫是大型商品肉鸡场预防H9亚型禽流感较好的免疫程序,在42天的饲养期内抗体滴度一直维持在有效保护水平以上,能够较好的保护鸡群免受H9亚型禽流感病毒的感染。通过检测鸡舍空气细菌数,对3种消毒剂进行了空鸡舍消毒效果检测,结果表明,福尔马林、高锰酸钾熏蒸消毒和杜邦卫可喷雾消毒效果良好,福尔马林、高锰酸钾熏蒸消毒后为每立方米细菌数降低93.3%,杜邦卫可喷雾消毒后为每立方米细菌数降低92.7%;戊二醛喷雾消毒效果较差,消毒后为每立方米细菌数降低65.3%。
[Abstract]:In recent years, China's commercial chicken industry has developed rapidly. Comprehensive epidemic prevention is the key measure to ensure the healthy growth of commercial broilers. However, many commercial chicken farms lack standardized comprehensive prevention measures, Newcastle disease. The two major infectious diseases of avian influenza are unscientific immune procedures and irrational use of disinfection drugs which seriously affect the effectiveness of epidemic prevention and hinder the healthy development of broiler industry. Therefore, this study closely combined with the production of commercial broilers, carried out a commercial broiler Newcastle disease H9 subtype avian influenza immune program test and empty chicken house disinfection efficacy of different disinfection test. In order to establish a scientific and reasonable Newcastle disease and H9 subtype avian influenza immunization program suitable for the large commercial chicken farm, and to screen out the disinfection drugs suitable for the empty chicken house. To provide a technical reference for the establishment of comprehensive epidemic prevention measures in large-scale commercial chicken farms in China. The antibodies of chickens immunized with two different Newcastle disease immunization procedures were detected. The titer of maternal antibody of Newcastle disease was as high as 9.1 log2 at 2 days of age, and then decreased gradually after 7 days of age. The titer of antibody was lower than the critical value of protection (6log2) after 7 days of age. Seven days of age, the first 19 days of inactivated vaccine and 28 days of inactivated vaccine were the best immunization procedures for Newcastle disease, which was suitable for the large commercial chicken farm in which the test was conducted. The antibody titer was maintained above the effective protection level during the whole 42-day feeding period, which could protect chickens from Newcastle disease virus infection. The antibodies of chickens immunized with two different H9 subtypes of avian influenza were detected. The titer of maternal antibody against H9 subtype avian influenza reached 9.52 log2 at 2 days of age, and the titer of H9 subtype avian influenza maternal antibody was close to the protective critical value (4log2) at 11 days of age. One-dose immunization at 11-12 days old is a good immunization procedure for large commercial broiler farms to prevent H9 subtype avian influenza, and the antibody titer has been maintained above the effective protective level during the 42-day feeding period. It can protect chickens from the infection of H 9 subtype avian influenza virus. The results showed that formalin, potassium permanganate fumigation and DuPont were effective in disinfection of three kinds of disinfectants, formalin, potassium permanganate and DuPont. After fumigation with potassium permanganate, the number of bacteria per cubic meter was decreased by 93.3g / m3, the number of bacteria per cubic meter decreased by 92.7% after spraying disinfection, and the disinfection effect of glutaraldehyde spray was poor, the number of bacteria per cubic meter decreased by 65.3% after disinfection.
【学位授予单位】:内蒙古农业大学
【学位级别】:硕士
【学位授予年份】:2015
【分类号】:S858.31
【参考文献】
相关期刊论文 前10条
1 王龙涛;葛晨霞;黄雷;王丽丽;胡桂学;;鸡新城疫的诊断及病理分析[J];安徽农业科学;2010年30期
2 崔治中;;规模化肉鸡安全生产与免疫抑制性病毒多重感染的预防控制[J];山东畜牧兽医;2008年01期
3 陆海融,樊晓晖;禽流感病毒H9N2的研究进展[J];广西医学;2005年05期
4 陈云霞;刘华雷;管峰;郑东霞;赵云玲;王志亮;;Ⅰ类新城疫病毒NDV08-004株病毒拯救体系的建立[J];病毒学报;2012年05期
5 及连盈;宋春丽;徐海军;;应对禽流感的生物危害与防控研究进展[J];家禽科学;2012年01期
6 刘佃章;杨小燕;赖友辉;华绍桂;黄金兰;;禽流感(AI)H_9和新城疫二联灭活油佐剂疫苗的研制[J];龙岩学院学报;2005年06期
7 王学理;武迎红;鲁金波;原奎林;;新城疫病毒分子生物学研究进展[J];内蒙古民族大学学报(自然科学版);2009年03期
8 宋晓晖,王中立,孙明,陈西钊;禽流感防制研究进展[J];中国禽业导刊;2003年18期
9 贾松涛;刘星;刘炜;张凌燕;王辉;程遥;周婷婷;宋庆华;;不同免疫程序ND抗体消长规律及免疫保护临界值的测定[J];中国动物检疫;2010年09期
10 陈瑞爱,温志芬,唐满华,潘洪波,李琳;禽流感H_9亚型油乳剂灭活疫苗的改进[J];中国兽医科技;2004年01期
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