白虎定喘口服液的质量检测
发布时间：2018-10-08 11:13
【摘要】：为了建立白虎定喘口服液的质量检测标准,采用薄层色谱法(TLC)对处方中金银花、黄芩、知母、板蓝根进行鉴别;采用高效液相色谱法(HPLC)对黄芩中有效成分黄芩苷进行含量测定。结果表明,薄层色谱斑点清晰,分离度好,特异性强;在0.103mg/mL~0.824mg/mL范围内黄芩苷浓度与峰面积呈良好的线性关系,阴性对照无干扰,加样回收率平均为97.98%,精密度试验RSD为0.61%。说明建立的检测方法简便、准确、专属性强、重复性好,可对白虎定喘口服液的质量进行有效检测。
[Abstract]:In order to establish the quality standard of Baihu Dingchuan oral liquid, the prescription of Flos Lonicerae, Radix Scutellariae, Radix Anemarrhenae and Radix Isatidis were identified by TLC (TLC), and the content of baicalin in Scutellaria baicalensis was determined by high performance liquid chromatography (HPLC). The results showed that the spots of TLC were clear, the degree of separation was good, the specificity was strong, the linear relationship between baicalin concentration and peak area was good in the range of 0.103mg/mL~0.824mg/mL, the negative control had no interference, the average recovery was 97.98 and the precision test RSD was 0.61%. The established method is simple, accurate, specific and reproducible. It can be used to detect the quality of Baihu Dingchuan oral liquid.
【作者单位】： 山东省农业科学院家禽研究所;
【基金】：国家公益性行业(农业)科研专项经费项目(201303040-10) 山东省重点研发计划项目(2015GNC113004,2016GNC113007) 济南市金种子企业关键产品提升计划项目(201602085)
【分类号】：S853.7
本文编号：2256542
[Abstract]:In order to establish the quality standard of Baihu Dingchuan oral liquid, the prescription of Flos Lonicerae, Radix Scutellariae, Radix Anemarrhenae and Radix Isatidis were identified by TLC (TLC), and the content of baicalin in Scutellaria baicalensis was determined by high performance liquid chromatography (HPLC). The results showed that the spots of TLC were clear, the degree of separation was good, the specificity was strong, the linear relationship between baicalin concentration and peak area was good in the range of 0.103mg/mL~0.824mg/mL, the negative control had no interference, the average recovery was 97.98 and the precision test RSD was 0.61%. The established method is simple, accurate, specific and reproducible. It can be used to detect the quality of Baihu Dingchuan oral liquid.
【作者单位】： 山东省农业科学院家禽研究所;
【基金】：国家公益性行业(农业)科研专项经费项目(201303040-10) 山东省重点研发计划项目(2015GNC113004,2016GNC113007) 济南市金种子企业关键产品提升计划项目(201602085)
【分类号】：S853.7
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