犬C-反应蛋白在疾病诊疗中的应用
发布时间：2018-10-18 16:04
【摘要】：CRP (C-反应蛋白)是一种炎性标志物在感染和组织损伤时血液中快速并急剧升高的主要急性期蛋白之一,是重要的炎性因子。犬CRP的检测在国外兽医临床应用比较广泛。本文通过对2014年5月-2015年2月前来内蒙古农业大学教学兽医院就诊的患犬进行血清CRP测定,同时进行一般检查和相关指标的检测,比较CRP在犬不同疾病中的变化规律及与症状相关性,分析CRP变化趋势对疾病诊断和预后的临床意义,并评估CRP在围手术期的监测价值。结果表明,CRP比WBC对于感染的诊断更为灵敏,可用于细菌性感染的早期诊断,CRP在各类疾病中不受糖皮质激素影响,可以准确反映细菌感染程度,可用于需要糖皮质激素治疗的疾病临床效果的监测；CRP较为敏感,在病毒性疾病继发感染早期或经生物制剂治疗后仍会升高,可提示临床配合其他检测手段,对于疾病的诊断起到很大的辅助作用；CRP还可用于术后恢复和疾病转归的预测,以及监测手术有无继发感染。
[Abstract]:CRP (C-reactive protein) is one of the most important inflammatory cytokines, which increases rapidly and rapidly in the blood of infected and injured tissues. The detection of canine CRP is widely used in veterinary clinic abroad. In this paper, serum CRP was measured in dogs from May 2014 to February 2015 in the College of Teaching and Veterinary Medicine of Inner Mongolia Agricultural University. To compare the changes of CRP in dogs with different diseases and its correlation with symptoms, to analyze the clinical significance of CRP change trend in the diagnosis and prognosis of disease, and to evaluate the monitoring value of CRP in perioperative period. The results showed that CRP was more sensitive than WBC in the diagnosis of bacterial infection and could be used in the early diagnosis of bacterial infection. CRP was not affected by glucocorticoid in all kinds of diseases and could accurately reflect the degree of bacterial infection. It can be used to monitor the clinical effects of diseases requiring glucocorticoid treatment. CRP is more sensitive and can still increase in the early stage of viral diseases secondary infection or after treatment with biological agents. CRP can also be used to predict postoperative recovery and prognosis, and to monitor secondary infection.
【学位授予单位】：内蒙古农业大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：S854.43
本文编号：2279639
[Abstract]:CRP (C-reactive protein) is one of the most important inflammatory cytokines, which increases rapidly and rapidly in the blood of infected and injured tissues. The detection of canine CRP is widely used in veterinary clinic abroad. In this paper, serum CRP was measured in dogs from May 2014 to February 2015 in the College of Teaching and Veterinary Medicine of Inner Mongolia Agricultural University. To compare the changes of CRP in dogs with different diseases and its correlation with symptoms, to analyze the clinical significance of CRP change trend in the diagnosis and prognosis of disease, and to evaluate the monitoring value of CRP in perioperative period. The results showed that CRP was more sensitive than WBC in the diagnosis of bacterial infection and could be used in the early diagnosis of bacterial infection. CRP was not affected by glucocorticoid in all kinds of diseases and could accurately reflect the degree of bacterial infection. It can be used to monitor the clinical effects of diseases requiring glucocorticoid treatment. CRP is more sensitive and can still increase in the early stage of viral diseases secondary infection or after treatment with biological agents. CRP can also be used to predict postoperative recovery and prognosis, and to monitor secondary infection.
【学位授予单位】：内蒙古农业大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：S854.43
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