新型添加剂左旋肉碱对小鼠不同生长期的影响

发布时间：2018-11-15 20:07

【摘要】：为了研究左旋肉碱作为新型功能性添加剂在小鼠不同生长期的体重变化情况,试验将昆明小鼠随机分为高剂量组、低剂量组和空白对照组,通过在饮水中加入不同剂量的左旋肉碱,连续测定6周的体重,分离小鼠的心脏、肝脏、脾脏、肺脏、肾脏并称取重量。结果表明:高剂量组(♀)和对照组(♀)第2周体重差异显著(P0.05);高剂量组(♂)和对照组(♂)第1周和第6周体重差异显著(P0.05);低剂量组(♂)和对照组(♂)在第2周、第3周体重差异显著(P0.05),第4,5,6周体重差异极显著(P0.01);其他与对照组之间差异不显著(P0.05);无论是雌性小鼠还是雄性小鼠,高剂量组、低剂量组和对照组脏器重均无显著性差异(P0.05);脏器系数均无显著性差异(P0.05)。说明左旋肉碱对昆明小鼠在不同生长周期的生长性能有促进作用,脏器无特殊变化。
[Abstract]:In order to study the changes of body weight of mice with L-carnitine as a new functional additive in different growth stages, Kunming mice were randomly divided into high dose group, low dose group and blank control group. By adding different doses of L-carnitine to drinking water and measuring body weight for 6 weeks, the heart, liver, spleen, lung and kidney of mice were separated and weighed. The results showed that there were significant differences in body weight between the high dose group and the control group at the 2nd week (P0.05), the weight at the 1st week and the 6th week in the high dose group (P 0.05) and the control group (P 0.05). The weight difference between the low dose group and the control group was significant in the second week and the third week (P0.05), the weight difference in the 4th 5th week (P0.01) was extremely significant (P0.01), the difference between the other groups and the control group was not significant (P0.05). There was no significant difference in organ weight between female and male mice in high dose group, low dose group and control group (P0.05), but no significant difference in organ coefficient (P0.05). The results showed that L-carnitine could promote the growth performance of Kunming mice in different growth cycles, but had no special changes in viscera.
【作者单位】：贵州医科大学实验动物中心;
【基金】：贵州省科技厅基金项目(黔科合LH字[2014]7100) 贵州医科大学青年基金项目(K2010-27)
【分类号】：S816.7

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