比格犬蠕形螨病的诊疗与病理组织学观察

发布时间：2019-03-07 08:26

【摘要】：目的对感染蠕形螨的比格犬进行诊疗及病理组织学观察。方法直接涂片法进行显微镜检查,常规石蜡切片及HE染色后进行病理组织学观察。结果 (1)临床观察:患病犬四肢、眼周、下腹部等部位皮肤出现红点,患部脱毛,四肢皮肤变厚起皱褶;(2)血液常规检查:基本正常;(3)显微镜观察:发现大量犬蠕形螨小型虫体和虫卵;(4)病理组织学观察:毛囊内见大量犬蠕形螨虫体和虫卵,皮脂腺和汗腺结构正常,均未见螨体寄生。毛囊周围见大量嗜酸性粒细胞和嗜中性粒细胞浸润,同时可见多灶性肉芽肿形成,肉芽肿呈椭圆形;(5)治疗方案:采用联合用药进行治疗,加强环境控制,疗效显著。结论犬蠕形螨引起的肉芽肿可划分为免疫性肉芽肿;小型虫体感染后可能不会破坏皮脂腺,皮脂腺是否感染虫体可能与虫体种类或感染病程相关。
[Abstract]:Objective to study the diagnosis and treatment of Demodex infection in Beagle dogs. Methods Microscopy was performed by direct smear method, routine paraffin sections and HE staining were performed for histopathological observation. Results (1) Clinical observation: red spots appeared in the skin of the affected dogs such as extremities, periocular and lower abdomen, the affected part was depilated, the skin of the limbs became thicker and fold, (2) the blood routine examination: the basic normal; (3) microscopic observation: a large number of small bodies and eggs of Demodex canis were found, (4) histopathological observation: a large number of Demodex canis and eggs were found in hair follicles, sebaceous glands and sweat glands were normal, and no parasites were found. A large number of eosinophils and neutrophils infiltrated around the hair follicles, and multifocal granuloma was formed, and granuloma was oval. (5) the treatment plan: the combination of drugs was used to strengthen the environmental control, and the curative effect was remarkable. Conclusion granuloma caused by Demodex canis can be divided into immune granuloma, small worm infection may not destroy sebaceous gland, whether sebaceous gland infection may be related to the species or the course of infection.
【作者单位】：南京军区福州总医院比较医学科;福州动物缘宠物医院;
【基金】：福建省科技计划引导性项目(2015Y0075) 南京军区福州总医院临床应用研究专项(2015L01)
【分类号】：S858.292

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