芪楂口服液药渣对断奶仔猪生长性能和肠道健康的影响

发布时间：2019-07-02 15:01

【摘要】：为了探讨中药渣作为饲料原料或饲料添加剂的可行性,本试验选用21日龄断奶仔猪120头,随机分为对照组、芪楂口服液药渣组、发酵芪楂口服液药渣组和氧化锌组,比较研究发酵前和发酵后芪楂口服液药渣对断奶仔猪生长性能、营养物质消化率、肠黏膜形态结构和紧密连接蛋白mRNA相对表达量。每组5个重复,每个重复6头仔猪。试验期为28 d。结果表明:1)试验全期(第1~28天),发酵芪楂口服液药渣组仔猪的料重比低于对照组和芪楂口服液药渣组(P0.05),氧化锌组仔猪腹泻率显著低于其他各组(P0.05)。2)试验第28天,发酵芪楂口服液药渣组仔猪的干物质、粗脂肪和粗蛋白质消化率显著低于对照组(P0.05),粗脂肪消化率显著低于芪楂口服液药渣组(P0.05),粗蛋白质消化率显著低于氧化锌组(P0.05)。3)发酵芪楂口服液药渣组仔猪空肠、回肠绒毛高度和绒毛高度/隐窝深度值大于芪楂口服液药渣组(P0.05),绒毛宽度和隐窝深度小于芪楂口服液药渣组(P0.05)。4)各组空肠、回肠和结肠闭锁蛋白和紧密连接相关蛋白-1的mRNA相对表达量无显著差异(P0.05)。综上所述,与芪楂口服液药渣相比,发酵芪楂口服液药渣可在一定程度上改善断奶仔猪肠道形态结构,二者对紧密连接蛋白mRNA相对表达量没有显著影响。
[Abstract]:In order to investigate the feasibility of traditional Chinese medicine residue as feed raw material or feed additive, 120 weanling piglets of 21 days old were randomly divided into control group, Qicaowu oral liquid residue group and zinc oxide group. The growth performance, nutrient digestibility, intestinal mucous membrane morphology and relative expression of tight junction protein mRNA in weanling piglets were compared before and after fermentation. There were 5 repeats in each group and 6 piglets in each group. The experimental period was 28 days. The results showed that: 1) the feed weight ratio of piglets in fermented Qicaowang oral liquid residue group was lower than that in control group and Qicaowu oral liquid residue group (P 0.05), and the diarrhea rate in zinc oxide group was significantly lower than that in other groups (P 0.05). 2) on the 28th day of experiment, the digestibility of dry matter, crude fat and crude protein in fermented Qicaowao oral liquid residue group was significantly lower than that in control group (P 0.05). The digestibility of crude fat was significantly lower than that of Qitaowu oral liquid residue group (P 0.05), and the digestibility of crude protein was significantly lower than that of zinc oxide group (P 0.05). 3) the height of ileal villi and villi height / crypt depth in fermented Qicaowao oral liquid residue group were significantly higher than those in Qitao oral liquid residue group (P 0.05), and the width and depth of villi and recess in each group were lower than those in Qitao oral liquid residue group (P 0.05). 4) in each group, There was no significant difference in the relative expression of mRNA between ileum and colon atresia protein and tight junction related protein-1 (P 0.05). To sum up, compared with Qicaowang oral liquid residue, fermented Qicaowai oral liquid residue can improve the intestinal morphology and structure of weanling piglets to a certain extent, and they have no significant effect on the relative expression of tight junction protein mRNA.
【作者单位】：河南科技大学动物科技学院;中国科学院亚热带农业生态研究所湖南省畜禽健康养殖工程技术研究中心农业部中南动物营养与饲料科学观测实验站;湖南省植物功能成分利用协同创新中心;
【基金】：湖南省战略性新兴产业科技攻关项目(2014GK1007) 中央驻湘科研机构技术创新发展专项(2013TF3006) 中国工程院咨询研究项目(2015-XY-41)
【分类号】：S828.5

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