高危型人乳头瘤病毒负荷量与宫颈病变的关系研究

发布时间：2018-02-03 18:50

本文关键词： 高危型人乳头瘤病毒宫颈病变负荷量诊断价值　出处：《临床医学研究与实践》2017年27期 　论文类型：期刊论文

【摘要】：目的探讨高危型人乳头瘤病毒负荷量与宫颈病变的关系。方法选择2013年10月至2016年10月在我院妇科进行高危型人乳头瘤病毒负荷量检测的2 538例患者,按照患者病毒负荷量将其分为三组:1~100 pg/mL设为A组;101~500 pg/mL设为B组;500 pg/mL设为C组。统计和记录796例阳性感染病变患者的宫颈病变情况。结果 796例阳性感染病变患者中,经病理检查确诊为412例。其中,宫颈炎253例,宫颈上皮内瘤变150例,宫颈癌9例。在宫颈病变患者中,相比宫颈炎和上皮内瘤变,宫颈癌的HPV负荷量最高(P0.05);C组的宫颈癌发病率明显高于A、B组,差异具有统计学意义(P0.05)。结论高危型人乳头瘤病毒负荷量和宫颈病变有着密切的关系,且随着患者年龄的增加,出现宫颈瘤样变和癌变的风险越大。
[Abstract]:Objective to investigate the relationship between high risk human papillomavirus load and cervical lesions. Methods the high risk human papillomavirus load was detected in gynecology department of our hospital from October 2013 to October 2016. 538 patients. According to the viral load, the patients were divided into three groups: 1: 100 pg/mL as group A; 101 pg/mL was set up as group B; #number0# pg/mL was set up as group C. the cervical lesions of 796 patients with positive infection were counted and recorded. Results there were 796 patients with positive infection. 412 cases were confirmed by pathological examination, including 253 cases of cervicitis, 150 cases of cervical intraepithelial neoplasia and 9 cases of cervical carcinoma. The HPV load of cervical cancer was the highest (P 0.05). The incidence of cervical cancer in group C was significantly higher than that in group A (P 0.05). Conclusion there is a close relationship between the high risk type of human papillomavirus load and cervical lesions. The risk of cervical neoplasia and carcinogenesis increases with age.
【作者单位】：陕西省商洛市镇安县人民医院妇产科;陕西省商洛市镇安县云盖寺镇中心卫生院计划生育科;
【分类号】：R737.33
【正文快照】： 高危型人乳头瘤病毒(HPV)感染是宫颈癌及其他癌前病型人乳头瘤病毒负荷量检测的2 538例患者为研究对象。其变发生的主要危险因子[1]。宫颈病变也是临床常见疾病,不仅中,患者年龄在23~71岁,平均年龄在(38.9±1.5)岁;体重在影响了女性患者的生活质量,还增加了患者及其家属的负担

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