需氧菌性阴道炎诊断方法与影响因素的临床分析
发布时间:2018-03-23 12:26
本文选题:需氧菌性阴道炎 切入点:诊断 出处:《山西医科大学》2017年硕士论文
【摘要】:目的:通过对需氧菌性阴道炎(aerobic vaginitis,AV)诊断方法及影响因素的探究,比较不同诊断方法的检出结果、明确高危因素及保护因素,从而提高临床医生对需氧菌阴道炎的认知,加强诊断能力、规避危险因素,降低感染情况的发生,提高女性的生活品质。方法:收集2016年4月—12月在山西医科大学附属第一医院妇科住院的患者,术前常规行阴道分泌物检查共934例,筛除与本实验无关的阴道炎疾病528例,剩余406例样本分别采用Donders湿片法和五项酶联合试剂盒对需氧菌性阴道感染做出诊断。根据实验室结果,对试剂盒法诊断出的无异常发现和单一需氧菌阴道炎患者进行调查,内容包括年龄、学历、个人卫生习惯、性生活习惯等方面,同时就影响AV的危险因素与临床症状进行相关性分析。结果:1.采用Donders湿片法诊断为单一需氧菌性阴道炎患者共198例,采用五项酶联合试剂盒诊断为单一需氧菌性阴道炎212例。通过SPSS17.0统计学软件分析,两种方法对于检出单一需氧菌性阴道炎方面不存在差异,差别无统计学意义(P=0.065,P0.05),在检出AV方面较为一致,Kappa=0.754。2.50岁以上女性(OR 4.896,95%CI 2.452 9.777),长期使用护垫(OR 4.389,95%CI2.277-8.459),频繁的阴道冲洗习惯(OR 1.727,95%CI 1.049-2.845)是AV的独立危险因素。3.大专学历以上(OR 0.594,95%CI 0.370 0.954),单独清洗内衣裤(OR 0.126,95%CI 0.059-0.267)是AV的独立保护因素。4.AV的危险因素与临床症状严重程度有显著相关性,呈正相关(r=0.608,P0.001)。结论:1.两种诊断方法对于需氧菌性阴道炎的诊断基本一致,可根据需要选择合适的方法进行诊断。2.在妇科住院的患者中,50岁以上、频繁的阴道冲洗以及长期使用护垫人群更容易发生需氧菌性阴道炎。3.影响AV的危险因素越多,其临床症状可能越严重,应尽可能规避危险因素,建立优质生活。
[Abstract]:Objective: to investigate the diagnostic methods and influencing factors of Aerobic vaginitis vaginitis (AVV), compare the results of different diagnostic methods, and identify the high risk factors and protective factors, so as to improve the clinicians' understanding of aerobic vaginitis. To strengthen diagnostic ability, avoid risk factors, reduce the incidence of infection, and improve the quality of life of women. Methods: the patients hospitalized in the first affiliated Hospital of Shanxi Medical University from April to December 2016 were collected. A total of 934 cases of vaginal discharge were examined before operation, 528 cases of vaginitis which were not related to this experiment were screened out. The remaining 406 samples were diagnosed by Donders wet sheet method and five enzyme kit respectively. According to the laboratory results, we investigated the patients with no abnormal detection and single aerobic vaginitis diagnosed by the kit method. The contents include age, educational background, personal hygiene habits, sexual habits and so on. At the same time, the risk factors affecting AV and clinical symptoms were analyzed. Results: 1. A total of 198 patients with single aerobic vaginitis were diagnosed by Donders wet film method. 212 cases of single aerobic vaginitis were diagnosed by five enzyme kits. There was no difference between the two methods in the detection of single aerobic vaginitis by SPSS17.0 software. There was no significant difference in AV detection. The odds ratio (OR 4.89695) of CI 2.452 was 4.89695% for women over 0.754.2.50 years old, OR 4.389C95 CI2.277-8.459 for long-term use, frequent vaginal washing habit OR 1.72795CI 1.049-2.845) was the independent risk factor of AV. The odds ratio (OR 0.59495 CI 0.370 0.954) of AV was higher than that of junior college degree (OR 0.59495 CI 0.370 0.954), and the risk factor of AV was 1.72795CI 1.049-2.845 (OR = 0.59495 CI 0.370 0.954), and the risk factor of AV was 1.72795CI 1.049-2.845. OR 0.126 / 95 CI 0.059-0.267) is an independent protective factor of AV. 4. The risk factors of AV are significantly correlated with the severity of clinical symptoms. Conclusion [WT5HZ] [WT5BZ] [WT5BZ] [WT5BZ] [WT5BZ] [WT5BZ] the two diagnostic methods are basically the same in the diagnosis of aerobic vaginitis, and the appropriate methods can be selected for diagnosis according to the need. The more risk factors affecting AV, the more serious the clinical symptoms may be. It is necessary to avoid risk factors as much as possible and establish a good quality of life.
【学位授予单位】:山西医科大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R711.31
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