老年恶性卵巢肿瘤患者血清甲状腺激素水平及意义

发布时间：2018-04-14 00:34

本文选题：甲状腺功能减退 + 甲状腺激素　；参考：《中国老年学杂志》2017年14期

【摘要】：目的探讨老年恶性卵巢肿瘤患者血清甲状腺激素水平及意义。方法选择60例恶性卵巢肿瘤患者(恶性组)、30例良性卵巢肿瘤患者(良性组)为研究对象,采用化学发光法测定两组患者血清甲状腺激素水平。结果恶性组患者血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平显著低于良性组,促甲状腺素(TSH)水平显著高于良性组(t=5.307、6.703、10.730,P0.05)。恶性卵巢肿瘤患者甲亢组与甲功正常组比较,FT3、FT4及TSH水平显著降低(t=2.849、7.973、10.733,P0.05);甲减组与甲功正常组比较,FT3、FT4水平显著降低,TSH水平显著上升(t=4.461、8.394、13.842,P0.05);甲减组与甲亢组比较,FT3、FT4水平明显降低,而TSH明显上升(t=2.630、4.686、11.744,P0.05)。结论甲状腺激素水平与老年妇女恶性卵巢肿瘤的发生密切相关,对评估卵巢肿瘤的性质、判断病情和评价预后意义重大。
[Abstract]:Objective to investigate the serum thyroid hormone level and its significance in elderly patients with malignant ovarian tumors.Methods 60 patients with malignant ovarian tumor (malignant group, 30 patients with benign ovarian tumor) were selected as study subjects. The serum thyroid hormone levels were measured by chemiluminescence assay in two groups.Results the serum levels of free triiodothyronine (FT3) and free thyroxine (FT4) in malignant group were significantly lower than those in benign group, and the level of thyrotropin TSH4 in malignant group was significantly higher than that in benign group.The levels of FT3T4 and TSH in hyperthyroidism group were significantly lower than those in normal group, and the levels of FT3T4 in hypothyroidism group were significantly lower than those in normal group, and the levels of FT3T4 in hypothyroidism group were significantly lower than those in hyperthyroidism group (P 0.05), and the levels of FT3FT4 in hypothyroidism group and hyperthyroidism group were significantly lower than those in hypothyroidism group and hypothyroidism group, and the level of FT3FT4 in hypothyroidism group was significantly lower than that in hyperthyroidism group.However, TSH increased significantly (2.630) 4.686 (11.744C) (P0.05).Conclusion thyroid hormone level is closely related to the occurrence of malignant ovarian tumors in elderly women. It is of great significance to evaluate the nature of ovarian tumors, to judge the state of the disease and to evaluate the prognosis.
【作者单位】：神农架林区人民医院;湖北省远安县人民医院;三峡大学医学院;三峡大学生物与制药学院;
【基金】：湖北省卫计委科研项目(WJ2015MB285)
【分类号】：R737.31

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