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宫颈上皮内瘤变诊治的相关研究进展

发布时间:2018-04-22 06:24

  本文选题:宫颈上皮内瘤样病变 + 宫颈肿瘤 ; 参考:《国际妇产科学杂志》2016年04期


【摘要】:宫颈上皮内瘤变(CIN)是与宫颈癌密切相关的癌前病变。随着宫颈癌生物学研究的进展和筛查技术的进步,宫颈癌的筛查目标已转变为早期检出高级别CIN并行阻断性治疗。在CIN治疗策略的原则中,首要目的应是预防宫颈癌的发生。目前CIN的诊断仍依靠宫颈细胞学、阴道镜与组织病理学这三阶梯技术("three step"technique)。治疗方面,推荐期待治疗作为CINⅠ女性的标准治疗。对于CINⅡ与CINⅢ,宫颈环形电切术(LEEP)和激光锥切是推荐的治疗方法。术后主要通过细胞学、人乳头瘤病毒(HPV)检测对低至中度疾病残留及复发风险患者进行随访,对高度疾病残留及复发风险患者,推荐阴道镜随诊。现拟从CIN的诊断、转归、治疗、CIN合并妊娠、CIN治疗后对妊娠结局的影响以及随访等方面进行综述。
[Abstract]:Cervical intraepithelial neoplasia (cin) is a precancerous lesion closely related to cervical cancer. With the progress of biological research and screening technology of cervical cancer, the goal of cervical cancer screening has been transformed into the early detection of high-level CIN and blocking therapy. In the principle of CIN treatment strategy, the primary purpose should be to prevent the occurrence of cervical cancer. At present, the diagnosis of CIN still depends on the three-step technique of cervix cytology, colposcopy and histopathology ("three step" technique). In terms of treatment, expectant treatment is recommended as the standard treatment for CIN 鈪,

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