新疆墨玉县维吾尔族妇女宫颈高级别病变（≥CINⅡ）的相关因素分析

发布时间：2018-05-03 13:43

本文选题：宫颈癌 + 维吾尔族　；参考：《新疆医科大学》2014年硕士论文

【摘要】：目的：通过对新疆墨玉县维吾尔族妇女宫颈组织病理诊断≥CIN Ⅱ的发病高危因素的分析并了解其高危人群,为宫颈病变的防治提供理论依据。方法：根据墨玉县地理位置、人口分布、经济状况,抽取4个乡1个镇21-60岁的已婚妇女5000人作为调查对象,自2013年5月15日至2013年9月15日期间,采用访谈方式进行妇女基本信息的问卷调查、妇科检查、care HPV检测、TCT检测,care HPV阳性、TCT结果为ASCUS及以上病变和AGC者行阴道镜下宫颈活检,对病理结果CIN Ⅱ以上(包括CINⅡ和CGIN)妇女的年龄、生活习惯、婚育史、初次性交年龄等资料进行单因素、多因素的统计分析。结果：(1)5000个妇女中,HPV阳性者421人,检出率8.4%；其中45岁以上的妇女HPV阳性率较高,TCT阳性者(为ASCUS以上者,包括ASCUS和AGC)222人,检出率4.4%；HPV与TCT任意一个阳性者为545人,检出率10.9%。(2)单因素分析结果显示,妇女的年龄、HPV感染、结婚次数与CIN的发生之间的关联有统计学差异,HPV感染、年龄的增长、结婚次数的增多会增加发生宫颈病变的可能性。(3)多因素分析结果,妇女的年龄、HPV感染与≥CINⅡ均有统计学意义。结论：(1)本项研究显示,45岁以上的妇女HPV和宫颈病变的检出率均较高,高危型HPV阳性的妇女,需警惕子宫颈癌前病变甚至是宫颈癌的存在。(2)年龄和HPV感染是维吾尔族妇女患≥CINⅡ级的高危因素,这部分人群应作为重点筛查人群。
[Abstract]:Objective: to provide a theoretical basis for the prevention and treatment of cervical lesions through the analysis of the high risk factors for the pathological diagnosis of the cervical tissue of Uygur women in the Xinjiang Moyu County, which is more than CIN II, and to provide a theoretical basis for the prevention and treatment of cervical lesions. Methods: according to the geographical location, population distribution and economic status of the Moyu County, 5000 married women of 21-60 years old in 1 towns of 4 townships were selected as the basis. For the survey, from May 15, 2013 to September 15, 2013, questionnaires were conducted on basic information of women, gynecologic examination, care HPV test, TCT test, care HPV positive, TCT results for ASCUS and above pathological changes and cervical biopsy under colposcopy for AGC, and the pathological results were above CIN II (CIN II and CGIN) women. The data of age, life habit, marriage and breeding history and the age of first sexual intercourse were analyzed. Results: (1) among 5000 women, 421 were HPV positive, and the detection rate was 8.4%; among them, the positive rate of HPV was higher in women over 45 years of age, and 222 of TCT positive (above ASCUS, including ASCUS and AGC), 4.4%, HPV and TCT The positive rate was 545, and the detection rate of 10.9%. (2) single factor analysis showed that there were statistical differences between women's age, HPV infection, marriage times and the occurrence of CIN. HPV infection, age, marriage times increased the availability of cervical lesions. (3) multifactor analysis, women's age, HPV infection and > C IN II all have statistical significance. Conclusions: (1) this study showed that the detection rate of HPV and cervical lesions in women over the age of 45 years old was higher, and the women with high risk type HPV positive should be alert to the existence of cervical precancerous lesions and even cervical cancer. (2) age and HPV infection are the high risk factors for the Uygur women with CIN grade II. This part of the population should be made. To focus on screening people.

【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.33

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