重庆地区计划妊娠妇女弓形虫感染现况调查

发布时间：2018-06-06 15:15

本文选题：计划妊娠 + 弓形虫感染　；参考：《中国人兽共患病学报》2015年03期

【摘要】：目的了解重庆地区计划妊娠妇女弓形虫感染现况,为本区域出生缺陷一级干预提供参考依据。方法采用按比例多阶段分层整群随机抽样方法抽取11 953例计划妊娠妇女进行问卷调查,并采集静脉血,用ELISA法检测弓形虫特异性抗体。结果 11 953例妇女中,弓形虫IgM阳性71例,阳性率0.59%;IgG阳性771例,阳性率6.45%。一圈地区弓形虫IgM阳性率、IgG阳性率均高于渝东南和渝东北地区(χ2=35.28,P0.000 1;χ2=82.65,P0.000 1)。弓形虫IgM阳性率随文化程度升高而升高(χ2趋势=3.25,P=0.0011)。不同职业妇女弓形虫IgM阳性率、IgG阳性率不同(χ2=13.93,P=0.016 0;χ2=15.58,P=0.008 1),IgM阳性率和IgG阳性率均公职人员最高。既往有不良妊娠结局史的计划妊娠妇女,弓形虫IgM阳性率、IgG阳性率高于对照组(χ2=6.85,P=0.008 9;χ2=59.25,P0.000 1)。密切接触猫的计划妊娠妇女弓形虫IgM阳性率和对照组无统计学差异(χ2=0.23,P=0.628 6),IgG阳性率高于对照组(χ2=9.95,P=0.001 6)。结论重庆地区计划妊娠妇女弓形虫感染率处于较低水平,不良妊娠结局与弓形虫感染有关。
[Abstract]:Objective to investigate the status of Toxoplasma gondii infection in pregnant women in Chongqing, and to provide reference for primary intervention of birth defects. Methods A total of 11 953 pregnant women with planned pregnancy were selected by proportional and multistage stratified cluster random sampling. Venous blood samples were collected, and specific antibodies against Toxoplasma gondii were detected by Elisa. Results among 11 953 women, 71 cases were positive for Toxoplasma IgM and 771 cases were positive for IgG, the positive rate was 6.45%. The positive rates of Toxoplasma gondii IgM and IgG in the first circle were higher than those in the southeast and northeast of Chongqing (蠂 ~ 2 ~ 2 ~ (35.28) P _ (0.000 1), 蠂 ~ (2 +) 82.65) P 0.000 ~ (1). The IgM positive rate of Toxoplasma gondii increased with the increase of educational level (蠂 ~ 2 trend: 3.25%, P < 0.0011). The positive rates of Toxoplasma IgM and IgG were different among different occupation women (蠂 ~ 2 ~ 2 ~ (13. 93) P ~ (+) P ~ (0.0160), 蠂 ~ (2) ~ (15.58) P ~ (1) P ~ (0.008) ~ (1) ~ +) IgM positive rate and IgG positive rate were the highest in public servants. The positive rate of Toxoplasma gondii IgM and IgG in the planned pregnant women with history of adverse pregnancy outcome was higher than that in the control group (蠂 2, 6.85, P = 0.008 9, 蠂 2, 59.25, P 0.000 1, P = 0.000 1). There was no significant difference in the positive rate of Toxoplasma IgM between the pregnant women with close contact with cats and the control group (蠂 2 + 0.23%, P = 0.628 6), and the positive rate of IgG was higher than that of the control group (蠂 ~ (2) 9.95% P ~ (0.001). Conclusion the infection rate of Toxoplasma gondii in planned pregnant women in Chongqing is at a low level, and the adverse pregnancy outcome is related to Toxoplasma gondii infection.
【作者单位】：重庆市人口和计划生育科学技术研究院技术指导所国家卫生计生委出生缺陷与生殖健康重点实验室;
【基金】：重庆市科学技术委员会科技攻关项目(CSTC2013ggB0012) 重庆市人口和计划生育科学技术研究院基本科研业务费项目(1207)~~
【分类号】：R714.251

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