重庆地区妊娠妇女TORCH感染的调查研究

发布时间：2018-07-29 13:22

【摘要】：目的了解妊娠妇女TORCH感染现况,为预防新生儿出生缺陷干预提供参考依据。方法 2013年4-12月采用按比例多阶段分层整群随机抽样方法,抽取11 953例符合生育政策、计划在3个月内怀孕的妊娠妇女进行问卷调查,采集其静脉血,用ELISA法检测TORCH特异性抗体。结果 11 953例妊娠妇女中巨细胞感染率为0.38%、弓形体为0.59%、梅毒为0.89%;其中渝东南地区(6个区县)巨细胞感染率最高为1.19%、一圈地区(22个区县)弓形体感染率最高为0.94%、渝东北地区(11个区县)梅毒感染率最低为0.23%;梅毒感染率随年龄增加而升高,弓形体感染率随文化程度升高而升高,梅毒感染率随着文化程度升高而下降;不同职业妇女弓形体感染率不同,公职人员最高为1.06%、农民最低为0.37%;既往具有不良妊娠结局史的计划妊娠妇女巨细胞、弓形体、梅毒阳性率均高于对照组。结论重庆地区妊娠妇女弓形体、巨细胞感染率处于一般水平,梅毒感染率较高,不良妊娠结局与TORCH感染有关,进行TORCH检查对优生优育有重要意义。
[Abstract]:Objective to investigate the status of TORCH infection in pregnant women and to provide reference for prevention of neonatal birth defects. Methods from April to December 2013, 11 953 pregnant women who were in line with the fertility policy were selected by the method of multistage stratified cluster random sampling, and their venous blood was collected by questionnaire survey, which was planned to be pregnant within 3 months. TORCH specific antibody was detected by ELISA method. Results among 11 953 pregnant women, the infection rate of giant cell was 0.38, Toxoplasma gondii 0.59m and syphilis 0.89.The infection rate of giant cells in southeast Chongqing (6 districts and counties) was 1.19, the highest infection rate of Toxoplasma gondii in one circle (22 districts and counties) was 0.94, and that in Chongqing was 0.89. The lowest rate of syphilis infection in Northeast China (11 districts and counties) was 0.23.The syphilis infection rate increased with age. The infection rate of Toxoplasma gondii increased with the increase of education, and the infection rate of syphilis decreased with the increase of education. The highest for public servants was 1.06 and the lowest for farmers was 0.37.The positive rates of giant cells, toxoplasmosis and syphilis in planned pregnant women with a history of adverse pregnancy outcome were higher than those in the control group. Conclusion the infection rate of Toxoplasma gondii and syphilis is high in pregnant women in Chongqing area. The adverse pregnancy outcome is related to TORCH infection. TORCH examination is of great significance to eugeny and eugeny.
【作者单位】：重庆市人口和计划生育科学技术研究院技术指导所;
【基金】：重庆市科学技术委员会科技攻关基金项目(CSTC2013GGB00001) 重庆市人口和计划生育科学技术研究院基金项目(2014CSTC-JBKY-01705)
【分类号】：R714.25

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