COOK球囊用于高龄初产孕妇足月引产的临床疗效观察

发布时间：2018-10-15 21:06

【摘要】：目的探讨COOK球囊用于高龄孕妇足月引产促宫颈成熟的有效性和安全性。方法回顾分析江门市新会区妇幼保健计划生育服务中心、广州市南方医科大学南方医院2015年1月至2016年3月50例应用COOK球囊引产的高龄孕妇资料,同时以50例同期COOK球囊引产的非高龄孕妇资料为对照。统计两组年龄、孕周、孕产次、引产指征、引产前后宫颈Bishop评分、产程时间、剖宫产指征及分娩结局,比较两组间差异。结果两组孕妇除年龄外,引产孕周、孕次、产次比较均无统计学意义。妊娠期糖尿病在高龄组孕妇中所占的比例显著高于非高龄组。单纯宫颈不成熟作为引产指征,非高龄组显著高于高龄组孕妇(P0.05)。高龄组孕妇应用球囊前后宫颈Bishop评分分别为(3.85±0.27)分、(5.76±1.33)分,应用球囊后显效及有效率为84.2%。非高龄组孕妇应用球囊前后宫颈Bishop评分分别为(4.27±0.48)分、(6.23±1.23)分,应用球囊后显效及有效率为87.5%。两组前后宫颈评分、有效率比较均无统计学差异。两组间第一产程、第二产程时间相比,高龄组长于非高龄组,有统计学意义。两组不良反应、剖宫产指征及分娩结局比较无统计学差异。结论 COOK球囊促宫颈成熟在高龄孕妇中的有效性和安全性与非高龄孕妇相当,对高龄孕妇是一种实用且安全的临床引产方法。
[Abstract]:Objective to evaluate the efficacy and safety of COOK balloon in term induction of cervix maturation. Methods the data of 50 elderly pregnant women who were induced labor by COOK balloon from January 2015 to March 2016 were analyzed retrospectively in the Maternal and Child Health and Family Planning Service Center of Xinhui District of Jiangmen City and the Southern Hospital of Southern Medical University of Guangzhou from January 2015 to March 2016. The data of 50 non-elderly pregnant women with COOK balloon induced labor at the same time were compared. The age, gestational weeks, times of pregnancy, indication of induced labor, Bishop score of cervix, time of labor, indication of cesarean section and the outcome of delivery were compared between the two groups. Results there was no significant difference between the two groups except age, gestational week, pregnancy and delivery. The proportion of gestational diabetes mellitus in the elderly group was significantly higher than that in the non-elderly group. Simple cervical immaturity as an indication of induced labor, the non-elderly group was significantly higher than the elderly group (P0.05). In the elderly group, the cervical Bishop scores were (3.85 卤0.27) and (5.76 卤1.33) before and after balloon application, respectively. The effective rate was 84.2%. The cervical Bishop scores were (4.27 卤0.48) and (6.23 卤1.23) before and after balloon application, respectively. The effective rate was 87.5%. There was no significant difference in the effective rate between the two groups before and after cervix score. The time of the first stage of labor and the second stage of labor between the two groups were significantly higher than that in the non-elderly group. There was no significant difference in adverse reactions, indications of cesarean section and delivery outcome between the two groups. Conclusion the efficacy and safety of COOK balloon in promoting cervix maturation in elderly pregnant women is similar to that in non-elderly pregnant women. It is a practical and safe clinical induction method for elderly women.
【作者单位】：江门市新会区妇幼保健计划生育服务中心;南方医科大学第二临床医学院;南方医科大学第一临床医学院;南方医科大学南方医院妇产科;
【基金】：江门市科技计划项目(2014020006126) 南方医科大学南方医院院长基金(2014B003) 国家自然科学基金(81401208)
【分类号】：R719.3

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