血清鳞癌相关抗原、糖类抗原125表达与宫颈癌临床分期的相关性
发布时间:2018-10-16 09:48
【摘要】:目的探讨宫颈鳞癌血清鳞癌相关抗原(SCC-Ag)及糖类抗原125(CA125)水平与临床病理参数的相关性。方法回顾性分析338例Ⅰ~Ⅳ期宫颈鳞癌患者的血清SCC-Ag及CA125水平,并对207例手术患者临床病理参数进行分析,探讨SCC-Ag及CA125表达水平与患者临床分期及病理参数之间的关系。结果 338例宫颈鳞癌患者中随着临床分期进展,SCC-Ag水平明显升高(P0.05),对207例手术患者中临床病理参数进行分析,发现SCC-Ag随着肿瘤体积的增大(P0.05)、淋巴结转移(P0.05)和肌层受侵深度的增加(P0.05),血清SCC-Ag值逐步升高,术后SCC-Ag水平明显下降(P0.05),且SCC-Ag在髂总淋巴结转移组表达水平明显高于仅盆腔淋巴结组。而CA125与宫颈鳞状细胞癌临床进展无明显差异(P0.05)。结论血清SCC-Ag可作为临床判断宫颈鳞癌分期及临床病理特征的重要标志物。
[Abstract]:Objective to investigate the correlation between serum squamous cell carcinoma-associated antigen (SCC-Ag) and carbohydrate antigen 125 (CA125) and clinicopathological parameters in squamous cell carcinoma of cervix (SCC). Methods the serum levels of SCC-Ag and CA125 in 338 patients with cervical squamous cell carcinoma in stage 鈪,
本文编号:2273973
[Abstract]:Objective to investigate the correlation between serum squamous cell carcinoma-associated antigen (SCC-Ag) and carbohydrate antigen 125 (CA125) and clinicopathological parameters in squamous cell carcinoma of cervix (SCC). Methods the serum levels of SCC-Ag and CA125 in 338 patients with cervical squamous cell carcinoma in stage 鈪,
本文编号:2273973
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