单纯性子痫前期与慢性高血压并发子痫前期的临床对比分析

发布时间：2018-11-21 15:15

【摘要】：目的单纯性子痫前期与慢性高血压并发子痫前期对母儿的影响。方法收集2009年1月至2015年6月于广州医科大学附属第三医院产科住院部分娩的、单胎、无合并其他基础疾病的妊娠期高血压疾病共596例临床资料进行回顾性分析,其中轻度子痫前期(MPE)101例、重度子痫前期(SPE)377例、慢性高血压并发子痫前期(CHPE)84例、妊娠合并慢性高血压(CHCP)34例。比较四组的一般情况、辅助检查结果、分娩情况及母儿结局。结果与MPE组、SPE组相比,CHPE组的年龄偏大(33.58±5.28),经产妇(69%)、双亲中至少一人患高血压者(31%)等比例大于单纯性子痫前期组。SPE组的尿酸值最高;CHPE组与SPE组的产前24 h尿蛋白差异无统计学意义,其剖宫产率高于MPE组及CHCP组,其终止妊娠时间早于MPE组和CHCP组。CHPE组与SPE组在新生儿体重、新生儿窒息率、Apgar评分等方面差异无统计学意义。CHPE组娩出活婴数量最少,新生儿中男婴所占比例大。结论与单纯性子痫前期相比,慢性高血压并发子痫前期孕妇的平均年龄大、高血压家族史比例高,辅助检查指标以及母儿结局与重度子痫前期相近。
[Abstract]:Objective to study the effect of simple preeclampsia and chronic hypertension complicated with preeclampsia on mother and infant. Methods from January 2009 to June 2015, a total of 596 cases of pregnancy-induced hypertension complicating hypertension were retrospectively analyzed in the department of obstetrics and obstetrics of the third affiliated Hospital of Guangzhou Medical University. Among them, 101 cases of mild preeclampsia (MPE), 377 cases of severe preeclampsia (SPE), 84 cases of chronic hypertension complicated with pre-eclampsia (CHPE), 34 cases of pregnancy complicated with chronic hypertension (CHCP). The general condition, the results of the auxiliary examination, the delivery condition and the maternal and infant outcome were compared among the four groups. Results compared with MPE group and SPE group, the age of CHPE group was older (33.58 卤5.28). The proportion of hypertensive patients with at least one parent (31%) in CHPE group was higher than that in simple preeclampsia group (31%). The uric acid value of SPE group was the highest. The rate of cesarean section in CHPE group and SPE group was higher than that in MPE group and CHCP group, and the termination time of pregnancy was earlier than that in MPE group and CHCP group. The neonatal weight and asphyxia rate in CHPE group and SPE group were higher than those in SPE group. There was no significant difference in Apgar score. In CHPE group, the number of live infants was the least, and the proportion of male infants was large. Conclusion compared with simple preeclampsia, the average age of pregnant women with chronic hypertension complicated with pre-eclampsia is higher, the proportion of hypertension family history is higher, the indexes of auxiliary examination and the maternal and infant outcome are similar to those of severe preeclampsia.
【作者单位】：广州医科大学附属第三医院;
【基金】：产科重大疾病防控创新团队(2015KCXTD020) 广州市教育局协同创新重大项目(13xt04) 广州市科技惠民专项项目(2014Y2-00182)
【分类号】：R714.24

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