绝经后子宫内膜息肉恶变与代谢综合征的关系初探
发布时间：2018-12-25 13:41
【摘要】：目的探讨绝经后子宫内膜息肉恶变与代谢综合征的关系,进而探讨其潜在恶变及恶变的危险因素,为代谢综合征患者的子宫内膜息肉的早期诊治提供理论依据。方法分析2006年1月-2013年1月该院妇产科收治的435例经宫腔镜病理确诊为子宫内膜息肉的患者,依据病理类型分为良性组(415例)和非典型增生(恶变组)(20例),对两组临床资料进行回顾性分析。结果子宫内膜息肉的恶变率4.6%,单因素分析,与子宫内膜息肉发生非典型增生或恶变的相关因素有体质指数(BMI)、绝经年限、绝经后阴道流血、子宫内膜厚度、腰围、空腹血糖、血三酰甘油(TG)、血高密度脂蛋白(HDL)(P0.05),多元回归分析后得出,BMI、腰围、舒张压、血TG、血HDL、空腹血糖或确诊为糖耐量异常或糖尿病是子宫内膜癌合并代谢综合征的独立危险因素(P0.05)。结论患有子宫内膜息肉的绝经妇女,子宫内膜息肉恶变与代谢综合征关系密切,建议绝经后有代谢综合征的子宫内膜息肉患者,应严密随访,如合并阴道流血、内膜厚度≥5 mm,息肉≥8 mm或息肉多发等高危因素,应在宫腔镜下切除息肉。
[Abstract]:Objective to investigate the relationship between endometrial polyp malignancy and metabolic syndrome after menopause, and to explore its potential malignant change and its risk factors, so as to provide theoretical basis for early diagnosis and treatment of endometrial polyps in patients with metabolic syndrome. Methods from January 2006 to January 2013, 435 cases of endometrial polyps diagnosed by hysteroscopic pathology were analyzed and divided into benign group (415 cases) and atypical hyperplasia group (20 cases). The clinical data of the two groups were analyzed retrospectively. Results the malignancy rate of endometrial polyps was 4.6%. Univariate analysis showed that the factors associated with atypical hyperplasia or malignant change of endometrial polyps were (BMI), menopausal age, postmenopausal vaginal bleeding, endometrial thickness, waist circumference. Fasting blood glucose, triacylglycerol (TG), serum high density lipoprotein (HDL) (P0.05), multiple regression analysis, BMI, waist circumference, diastolic blood pressure, blood TG, blood HDL, Fasting blood glucose or diagnosed impaired glucose tolerance or diabetes were independent risk factors for endometrial carcinoma with metabolic syndrome (P0.05). Conclusion in menopausal women with endometrial polyps, the malignant change of endometrial polyps is closely related to metabolic syndrome. It is suggested that patients with endometrial polyps with postmenopausal metabolic syndrome should be followed up closely, such as vaginal bleeding. Endometrial thickness 鈮，
本文编号：2391204
[Abstract]:Objective to investigate the relationship between endometrial polyp malignancy and metabolic syndrome after menopause, and to explore its potential malignant change and its risk factors, so as to provide theoretical basis for early diagnosis and treatment of endometrial polyps in patients with metabolic syndrome. Methods from January 2006 to January 2013, 435 cases of endometrial polyps diagnosed by hysteroscopic pathology were analyzed and divided into benign group (415 cases) and atypical hyperplasia group (20 cases). The clinical data of the two groups were analyzed retrospectively. Results the malignancy rate of endometrial polyps was 4.6%. Univariate analysis showed that the factors associated with atypical hyperplasia or malignant change of endometrial polyps were (BMI), menopausal age, postmenopausal vaginal bleeding, endometrial thickness, waist circumference. Fasting blood glucose, triacylglycerol (TG), serum high density lipoprotein (HDL) (P0.05), multiple regression analysis, BMI, waist circumference, diastolic blood pressure, blood TG, blood HDL, Fasting blood glucose or diagnosed impaired glucose tolerance or diabetes were independent risk factors for endometrial carcinoma with metabolic syndrome (P0.05). Conclusion in menopausal women with endometrial polyps, the malignant change of endometrial polyps is closely related to metabolic syndrome. It is suggested that patients with endometrial polyps with postmenopausal metabolic syndrome should be followed up closely, such as vaginal bleeding. Endometrial thickness 鈮，
本文编号：2391204
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