桂枝茯苓胶囊联合米非司酮治疗子宫肌瘤临床观察

发布时间：2019-03-12 17:51

【摘要】：目的:对联合应用桂枝茯苓胶囊及米非司酮治疗子宫肌瘤的临床价值进行分析。方法:将70例子宫肌瘤患者随机分为两组,以单纯接受米非司酮治疗者为对照组,以接受联合桂枝茯苓胶囊及米非司酮治疗者为观察组,每组35例,两组治疗前子宫体积、子宫肌瘤体积、卵巢刺激素(FSH)、黄体生成素(LH)及雌二醇(E2)比较无统计学意义。对比两组治疗前后子宫体积、子宫肌瘤体积、FSH、LH及E2水平变化情况进行对比,并对两组治疗有效率及药物副作用进行对比。结果:经治疗4个月后,观察组及对照组子宫体积、子宫肌瘤体积、FSH、LH及E2均明显改善(P0.05),观察组改善差值明显优于对照组改善差值(P0.05)。同时观察组治疗总有效率为94.28%,明显优于对照组的74.29%(χ2=5.2851,P=0.0215)。此外两组治疗期间药物副作用比较未见统计学差异(χ2=0.0945,P=0.7585)。结论:联合应用桂枝茯苓胶囊及米非司酮可显著提高子宫肌瘤的临床治疗效果。
[Abstract]:Objective: to analyze the clinical value of combined application of Guizhi Fuling capsule and mifepristone in the treatment of uterine leiomyoma. Methods: 70 patients with uterine leiomyoma were randomly divided into two groups. The control group was treated with mifepristone alone, the observation group was treated with Guizhi Fuling capsule and mifepristone. There were 35 cases in each group. There was no significant difference in the volume of uterine leiomyoma, (FSH), luteinizing hormone (LH) and estradiol (E2). The changes of uterine volume, myoma volume, FSH,LH and E _ 2 levels before and after treatment were compared between the two groups, and the effective rates and side effects of drugs were compared between the two groups. Results: after treatment for 4 months, the uterine volume, myoma volume, FSH,LH and E2 in the observation group and the control group were significantly improved (P0.05), and the improvement difference in the observation group was significantly better than that in the control group (P0.05). At the same time, the total effective rate of the observation group was 94.28%, which was significantly better than that of the control group (74.29%) (蠂 2 = 5.2851, P = 0.0215). There was no significant difference in side effects between the two groups during treatment (蠂 2 = 0.0945, P = 0.7585). Conclusion: combined application of Guizhi Fuling capsule and mifepristone can significantly improve the clinical therapeutic effect of uterine leiomyoma.
【作者单位】：泰顺县中医院妇产科;
【分类号】：R737.33

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