生长激素在高龄女性微刺激方案助孕中的运用研究
发布时间：2019-03-20 18:09
【摘要】：为了探讨高龄女性利用微刺激方案在助孕治疗周期中添加重组人生长激素(GH)的作用,本中心以84例高龄女性患者为研究对象(研究组加用GH组52例,对照组未加GH组32例),分析比较GH在微刺激方案助孕治疗过程对各项参数的影响。研究结果表明,研究组的促性腺激素(Gn)总用量和Gn使用天数均低于对照组,研究组的HCG日E2值、获卵数、MII数目、2PN数、卵裂期可利用胚胎数均高于对照组,其差异均具有显著性意义(P0.05);研究组的HCG日宫内膜厚度、受精率、卵裂率、优胚率稍高于对照组,但其差异均无显著性意义(P0.05)。因此,在微刺激方案中,加用GH对于卵巢低反应的高龄女性患者获益较大。
[Abstract]:In order to investigate the effect of recombinant human growth hormone (GH) (rhGH) on the treatment cycle of assisted pregnancy in elderly women, 84 elderly women (study group plus GH group, 52 cases) were enrolled in the study. Control group (n = 32) without GH (n = 32), the effects of GH on the parameters in the course of microstimulation therapy were analyzed and compared. The results showed that the total dosage of gonadotropin (Gn) and the duration of use of Gn in the study group were lower than those in the control group, and the E2 value, the number of eggs, the number of MII, the number of 2PN and the number of available embryos at cleavage stage in the study group were higher than those in the control group. The difference was significant (P0.05). The endometrial thickness, fertilization rate, cleavage rate and blastocyst rate of HCG in the study group were slightly higher than those in the control group, but there was no significant difference between the study group and the control group (P0.05). As a result, the use of GH in the microstimulus program benefited older women with low ovarian response.
【作者单位】： 湖南省计划生育研究所生殖中心;
【分类号】：R714.8
，
本文编号：2444475
[Abstract]:In order to investigate the effect of recombinant human growth hormone (GH) (rhGH) on the treatment cycle of assisted pregnancy in elderly women, 84 elderly women (study group plus GH group, 52 cases) were enrolled in the study. Control group (n = 32) without GH (n = 32), the effects of GH on the parameters in the course of microstimulation therapy were analyzed and compared. The results showed that the total dosage of gonadotropin (Gn) and the duration of use of Gn in the study group were lower than those in the control group, and the E2 value, the number of eggs, the number of MII, the number of 2PN and the number of available embryos at cleavage stage in the study group were higher than those in the control group. The difference was significant (P0.05). The endometrial thickness, fertilization rate, cleavage rate and blastocyst rate of HCG in the study group were slightly higher than those in the control group, but there was no significant difference between the study group and the control group (P0.05). As a result, the use of GH in the microstimulus program benefited older women with low ovarian response.
【作者单位】： 湖南省计划生育研究所生殖中心;
【分类号】：R714.8
，
本文编号：2444475
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