妊娠期糖尿病合并子痫前期的相关因素及妊娠结局分析

发布时间：2019-06-06 19:47

【摘要】：目的 :探讨妊娠期糖尿病合并子痫前期的相关因素及妊娠结局。方法 :选取2015年1—5月在南京市妇幼保健院住院分娩的无合并子痫前期的妊娠期糖尿病单胎孕妇98例为对照组,妊娠期糖尿病合并子痫前期孕妇68例为研究组。收集两组孕妇的体重指数(BMI)、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、甘油三酯(TG)、总胆固醇(TC)、尿酸(UA)、乳酸脱氢酶(LDH)、碱性磷酸酶(ALP)进行对比分析。同时比较两组的产后出血、剖宫产、早产、胎窘、胎膜早破、产间发热、羊水量情况、胎儿宫内生长迟缓(FGR)及巨大儿的发生率。结果:1研究组的BMI、FBG、TG、TC、UA均高于对照组,差异有统计学意义(P0.05);2研究组的产后出血、剖宫产、早产、胎窘、羊水过少、FGR的发生率高于对照组,差异有统计学意义(P0.05)。结论 :孕妇的体重指数、空腹血糖控制不理想、血甘油三酯、血胆固醇升高是妊娠期糖尿病合并子痫前期的相关风险因素,妊娠期糖尿病合并子痫前期将进一步增加母儿不良妊娠结局的发生。
[Abstract]:Objective: to investigate the related factors and pregnancy outcome of gestational diabetes mellitus complicated with preeclampsia. Methods: 98 pregnant women with gestational diabetes mellitus without preeclampsia and 68 pregnant women with gestational diabetes mellitus complicated with preeclampsia were selected as control group and 68 pregnant women with gestational diabetes mellitus complicated with preeclampsia from January to May 2015 in Nanjing Maternal and Child Health Hospital. Fasting blood glucose (FBG), glycosylated hemoglobin (Hb A1c) and total cholesterol (TC), uric acid (UA), lactic dehydrogenase (LDH), were collected in two groups of pregnant women with body mass index (BMI), fasting blood glucose and glycosylated hemoglobin (Hb A1c). Alkaline phosphatase (ALP) was compared and analyzed. At the same time, the incidence of postpartum hemorrhage, cesarean section, premature delivery, fetal embarrassment, premature rupture of membranes, parturient fever, amniotic fluid volume, fetal growth retardation (FGR) and macrosomia were compared between the two groups. Results: 1the BMI,FBG,TG,TC,UA of the study group was higher than that of the control group, the difference was statistically significant (P 0.05). 2 the incidence of postpartum hemorrhage, cesarean section, premature delivery, fetal embarrassment and oligoamniotic fluid in the study group was significantly higher than that in the control group (P 0.05). Conclusion: the body mass index (BMI) and fasting blood glucose (FBG) of pregnant women are not well controlled, and the increase of serum TG and cholesterol are the risk factors of gestational diabetes mellitus complicated with preeclampsia. Gestational diabetes mellitus complicated with preeclampsia will further increase the occurrence of adverse pregnancy outcomes in mothers and infants.
【作者单位】：南京医科大学附属南京妇幼保健院妇产科;
【分类号】：R714.256;R714.244

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