八珍汤加减联合抗菌药物治疗气血两虚型产后发热的临床观察

发布时间：2019-08-09 06:39

【摘要】：目的:探讨八珍汤加减联合抗菌药物治疗气血两虚型产后发热的临床疗效及安全性。方法:选取我院2014年12月-2016年6月收治的气血两虚型产后发热患者94例,按随机数字表法分为对照组和观察组,各47例。对照组患者给予注射用头孢唑林钠3 g加入氯化钠注射液250 m L中,ivgtt,bid;若连续2 d体温未下降,则给予注射用阿奇霉素250 mg加入氯化钠注射液250m L中,ivgtt,bid;体温超过38.5℃者肌内注射复方氨林巴比妥注射液2 m L。观察组患者在对照组基础上给予八珍汤加减治疗。两组患者疗程均为5 d。比较两组患者临床疗效及治疗前后白细胞计数、血浆C反应蛋白(CRP)、血浆黏度、血浆纤维蛋白原(Fib)水平,观察两组患者退热时间、住院时间及不良反应发生情况。结果:观察组患者总有效率为95.75%,显著高于对照组的78.72%,差异有统计学意义(P0.05)。治疗前,两组患者白细胞计数、CRP、血浆黏度、Fib水平比较,差异均无统计学意义(P0.05);治疗后,两组患者白细胞计数、CRP、血浆黏度、Fib水平均显著下降,且观察组水平显著低于对照组,差异均有统计学意义(P0.05)。观察组患者退热时间和住院时间均短于对照组,差异有统计学意义(P0.05)。观察组患者不良反应发生率为6.38%,显著低于对照组的23.40%,差异有统计学意义(P0.05)。结论:八珍汤加减联合抗菌药物治疗气血两虚型产后发热疗效显著,能明显改善患者炎症状态和血浆黏度,加快患者退热,且安全性高。
[Abstract]:Objective: to investigate the clinical efficacy and safety of Bazhen decoction combined with antibiotics in the treatment of postpartum fever with deficiency of qi and blood. Methods: from December 2014 to June 2016, 94 patients with postpartum fever with deficiency of both qi and blood were randomly divided into control group (n = 47) and observation group (n = 47). The control group was given cefazolin sodium 3 g and sodium chloride injection 250 mL. If the body temperature of ivgtt,bid; did not decrease for 2 days, azithromycin 250 mg and sodium chloride injection 250 mL were given intramuscular injection of compound aminobarbital injection 2 mL if the body temperature of cefazolin sodium for injection exceeded 38.5 鈩，

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