老年颅内动脉瘤患者血管内栓塞治疗的效果及影响因素

发布时间：2018-02-05 18:56

本文关键词： 颅内动脉瘤血管内栓塞　出处：《中国老年学杂志》2017年14期 　论文类型：期刊论文

【摘要】：目的探讨老年颅内动脉瘤患者血管内栓塞效果及影响治疗效果的相关因素。方法血管内栓塞治疗的112例老年颅内动脉瘤患者,根据数字减影全脑血管造影(DSA)判断动脉瘤栓塞效果,对比分析不同栓塞效果患者的临床资料,并采用Logistic回归分析影响老年患者颅内动脉瘤栓塞结果的可能因素。结果 112例患者经血管内介入栓塞术后,致密栓塞60例,非致密栓塞52例。单因素分析结果显示,致密栓塞组和非致密栓塞组性别、年龄、慢性病史、吸烟史、动脉瘤部位无统计学差异(P0.05),两组动脉瘤大小、形态、破裂状态、手术类型及术前Hunt-Hess分级均有统计学差异(P0.05)。多因素Logistic回归分析显示动脉瘤破裂状态、动脉瘤形态、大小、手术类型及Hunt-Hess分级均是影响老年颅内动脉瘤栓塞效果的独立因素。结论术前Hunt-Hess分级程度低,动脉瘤形态规则、体积偏小,术中采用支架辅助弹簧圈栓塞或球囊辅助弹簧圈栓塞均有利于动脉瘤的致密性栓塞,而患者动脉瘤破裂则不利于形成致密栓塞。
[Abstract]:Objective to investigate the effect of endovascular embolization in elderly patients with intracranial aneurysms and the related factors affecting the therapeutic effect. Methods 112 elderly patients with intracranial aneurysms were treated by endovascular embolization. The effect of aneurysm embolization was evaluated by digital subtraction angiography (DSAs), and the clinical data of patients with different embolization effects were compared and analyzed. Logistic regression analysis was used to analyze the possible factors influencing the results of intracranial aneurysm embolization in elderly patients. The results of univariate analysis showed that there was no significant difference in sex, age, chronic history, smoking history and aneurysm site between dense embolization group and non-dense embolization group (P 0.05). The size, shape and rupture state of the aneurysms were observed in both groups. The type of operation and preoperative Hunt-Hess grade were significantly different (P 0.05). Multivariate Logistic regression analysis showed the ruptured state, shape and size of aneurysm. The type of operation and Hunt-Hess grade were independent factors affecting the embolization of intracranial aneurysms in the elderly. Conclusion the preoperative Hunt-Hess grade is low, the shape of aneurysms is regular, and the volume is small. Stent assisted coil embolization or balloon assisted coil embolization was beneficial to the dense embolization of aneurysms, while the rupture of aneurysms was not conducive to the formation of dense embolization.
【作者单位】：许昌学院医学院;
【基金】：河南省医学教育研究课题(Wjlx2015193)
【分类号】：R651.12

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