健侧颈7神经根移位对全臂丛根性撕脱伤术后对侧运动皮层的远期影响

发布时间：2018-04-27 06:11

本文选题：臂丛 + 神经损伤　；参考：《立体定向和功能性神经外科杂志》2016年06期

【摘要】：目的观察健侧颈7移位术后2年运动皮层功能的重塑变化,以期从运动皮层功能重塑方面对临床远期随访的结果进行解释。方法 30只SD大鼠随机分为对照组、全臂丛根性撕脱伤组及颈7移位修复组,于术后24个月以微电极刺激技术检测各组大鼠患肢支配区在对侧大脑运动皮层的分布。结果术后24个月,对照组上肢支配区在大脑运动皮层的刺激位点数量在右侧为21.17±1.14个;在全臂丛根性撕脱伤组,颈部位点在术后两年仍占据着原前肢代表区;颈7移位术后左侧前肢代表区逐渐替代颈部位点,术后2年刺激位点数量为14.83±0.83。结论健侧颈7神经根移位治疗全臂丛根性撕脱伤能够引起成年大鼠对侧运动皮层远期的功能重塑。
[Abstract]:Objective to observe the remodeling of motor cortical function 2 years after normal cervical 7 transposition in order to explain the results of long-term clinical follow-up from the aspect of motor cortical function remodeling. Methods Thirty Sprague-Dawley rats were randomly divided into control group, total brachial plexus root avulsion group and cervical 7 transposition repair group. The distribution of innervation area of affected limb in contralateral motor cortex of rats was detected by microelectrode stimulation at 24 months after operation. Results 24 months after operation, the number of stimulation sites in the motor cortex of the control group was 21.17 卤1.14 on the right side, while in the group of total brachial plexus root avulsion, the cervical site still occupied the former forelimb representative area two years after operation. After cervical 7 transposition, the representative area of left forelimb gradually replaced the cervical site, and the number of stimulating sites was 14. 83 卤0. 83 after 2 years. Conclusion the treatment of total brachial plexus root avulsion injury by transposition of normal cervical 7 nerve root can induce long term functional remodeling of contralateral motor cortex in adult rats.
【作者单位】：上海交通大学医学院附属仁济医院骨科;
【基金】：上海市卫计委面上项目(编号:20124297)
【分类号】：R688

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