富血小板血浆与空心钉锁定钢板治疗股骨颈骨折

发布时间：2018-05-03 06:11

本文选题：富血小板血浆 + 股骨颈骨折　；参考：《中国矫形外科杂志》2017年14期

【摘要】：[目的]探讨富血小板血浆(PRP)与万向空心钉锁定钢板治疗股骨颈骨折的临床疗效。[方法]2012年1月~2015年1月本科收治60例股骨颈骨折患者,以单盲法按数字随机分为PRP联合万向空心钉锁定钢板治疗组(联合组)、单纯万向空心钉锁定钢板治疗组(单纯组),每组30例。对比两组患者手术时间、术中出血量、骨折愈合时间、完全负重所需时间、髋关节功能Haris评分、股骨头坏死发生率。[结果]两组患者手术时间、术中出血量比较差异无统计学意义(P0.05)。患者平均随访时间(18.82±4.21)个月,在完全负重所需时间[(10.32±1.84)个月vs(12.83±2.25),P0.001],骨折愈合时间[(9.47±2.64)个月vs(12.76±2.35)个月,P0.001],髋关节功能Harris评分[(90.12±5.34)vs(78.43±4.14),P0.001]方面联合组均显著优于单纯组,差异有统计学意义。联合组仅有1例患者发生股骨头坏死,而单纯组有3例发生股骨头坏死,但两组差异无统计学意义(P0.05)。[结论]PRP联合万向空心钉锁定板治疗青壮年股骨颈骨折可促进骨折愈合,具有固定牢靠、手术创伤小等优点。
[Abstract]:Objective: to investigate the clinical effect of platelet rich plasma (PRP) and universal hollow nail locking plate in the treatment of femoral neck fracture. [methods] from January 2012 to January 2015, 60 cases of femoral neck fracture were treated. According to the single blind method, the patients were randomly divided into PRP combined with universal hollow nail locking plate group (combined group) and simple universal hollow nail locking plate group (30 cases in each group). The operative time, intraoperative blood loss, fracture healing time, total weight bearing time, hip function Haris score, and the incidence of femoral head necrosis were compared between the two groups. [results] there was no significant difference in operative time and intraoperative bleeding between the two groups (P 0.05). The average follow-up time was 18.82 卤4.21 months, the time of complete weight loading was 10.32 卤1.84 months (vs(12.83 卤2.25) P0.001, the time of fracture healing was 9.47 卤2.64 months (vs(12.76 卤2.35) months P0.001, and the Harris score of hip joint function [90.12 卤5.34)vs(78.43 卤4.14P0.001] was significantly better than that of simple group (P 0.001). There was only one case of femoral head necrosis in the combined group and 3 cases in the simple group, but the difference between the two groups was not statistically significant (P 0.05). [conclusion] PRP combined with universal hollow nail locking plate in the treatment of femoral neck fracture in young adults can promote fracture healing, have the advantages of firm fixation and less surgical trauma.
【作者单位】：解放军第八十九医院创伤骨五科;山东省潍坊市昌邑人民医院手足外科;
【基金】：军队重点项目(编号:BJN13J001)
【分类号】：R687.32

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