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颞浅动脉-大脑中动脉分支吻合术结合脑-硬脑膜-颞肌血管融合术治疗成年烟雾病的临床疗效及高灌注综合征

发布时间:2018-10-23 17:37
【摘要】:目的探讨颞浅动脉-大脑中动脉分支吻合术结合脑-硬膜-颞肌血管贴敷融合术(STA-MCA+EDMS)治疗烟雾病手术早期效果及其高灌注综合征特点。方法通过回顾性分析符合纳入标准行STA-MCA+EDMS术的烟雾病患者临床资料。对比术前术后脑血管造影术结果;统计分析术前及术后6 m神经功能状态结果;分析术后高灌注综合征特征。结果 44人,共49次STA-MCA+EDMS术纳入本次研究;该术式能确切改善脑供血,颅内外血管形成良好交通;25人表示症状改善,但脑卒中临床神经功能缺损程度评分量表分析,评分虽有所改善,而无统计学意义;术后发生高灌注综合征等不良反应有18人(40.9%),而优势半球侧手术明显增加其发生概率(P0.05),Matsushima分型中Ⅲ~Ⅵ型潜在风险较高。结论临床上应根据烟雾病患者不同特征,进行有效术前评估及积极预后干预。
[Abstract]:Objective to investigate the early effect of superficial temporal arterio-middle cerebral artery anastomosis combined with brain-dura-temporal muscle application (STA-MCA EDMS) in the treatment of moyamoya disease and the characteristics of hyperperfusion syndrome. Methods the clinical data of patients with moyamoya disease were analyzed retrospectively. The results of preoperative and postoperative cerebrovascular angiography were compared, the results of 6 m nerve function before and after operation were statistically analyzed, and the characteristics of postoperative hyperperfusion syndrome were analyzed. Results Forty-four patients, 49 STA-MCA EDMS procedures, were included in the study. The procedure can improve the blood supply of brain and good communication between intracranial and external blood vessels. 25 patients indicated that symptoms were improved, but the clinical neurological deficit scale was used to evaluate the degree of cerebral apoplexy. There were 18 cases (40.9%) of adverse reactions such as hyperperfusion syndrome occurred after operation, while the probability of occurrence was significantly increased in dominant hemispheric surgery (P0.05). The potential risk of type 鈪,

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