局部应用氨甲环酸的全髋关节置换:回顾性分析不同时间引流量差异

发布时间：2018-11-04 08:03

【摘要】：背景:氨甲环酸局部应用于全髋关节置换可显著减少围手术期失血量,然而一直以来的研究重点在于关节置换后总引流量方面,对于置换后不同时间段内的引流量观察甚少。目的:观察局部应用氨甲环酸对全髋关节置换后不同时间的引流量的影响。方法:回顾性分析初次行单侧全髋关节置换的病例资料共79例,分为2组。试验组38例关节置换后经引流管逆行灌注氨甲环酸1.5 g(50 m L),对照组41例以同样方法灌注50 m L生理盐水。统计2组关节置换后第1,2,3天引流量、总引流量、置换后第3天血红蛋白。结果与结论:2组基线资料差异无统计学意义。(1)试验组置换后第1天引流量显著小于对照组(P0.05),第2,3天2组引流量差异无显著性意义(P0.05);试验组总引流量显著小于对照组(P0.05);(2)试验组置换后第3天血红蛋白显著高于对照组(P0.05);(3)结果表明,局部应用氨甲环酸可减少初次单侧全髋关节置换后引流量,尤以置换后第1天明显。
[Abstract]:Background: total hip replacement can significantly reduce blood loss in total hip replacement by local application of aminocyclylic acid. However, the focus of the study has been on the total drainage after arthroplasty, and little observation has been made on the drainage in different periods after replacement. Aim: to observe the effect of local application of carbamicylic acid on the drainage flow after total hip replacement (THR). Methods: 79 cases of primary total hip replacement were analyzed retrospectively and divided into 2 groups. After joint replacement, 38 patients in the test group were retrograde perfused with methocycline 1.5 g through drainage tube. 41 cases in 50 m L), control group were perfused with 50 mL normal saline in the same way. The drainage flow and the hemoglobin were calculated on the 1st day and 2nd day after arthroplasty in the two groups. Results and conclusion: there was no significant difference in baseline data between the two groups. (1) the drainage volume in the experimental group was significantly lower than that in the control group on the first day after replacement (P0.05), but there was no significant difference between the two groups on the 2nd day (P0.05). The total drainage volume in the trial group was significantly lower than that in the control group (P0.05); (2). The hemoglobin in the experimental group was significantly higher than that in the control group on the 3rd day after replacement (P0.05). (3) the results showed that local application of carbamoic acid could reduce the drainage volume after the first unilateral total hip replacement, especially on the first day after replacement.
【作者单位】：延安大学附属医院脊柱外科;
【基金】：陕西省社会发展科技攻关项目(2015SF115) 延安市科技惠民计划项目(2016HM-10-03)~~
【分类号】：R687.4

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