胃大部切除术对2型糖尿病患者血糖的影响

发布时间：2019-03-24 15:42

【摘要】：目的:探讨胃大部切除术对2型糖尿病患者血糖的影响。方法:回顾分析2009年~2014年间就诊于延安大学附属医院的99例合并糖尿病并进行胃大部分切除手术患者的临床资料,通过甄选后对45例临床资料完整、生存期相对比较长、无并发症并愿意配合采访的患者进行研究。根据患者术后血糖含量和控制血糖含量所需要的摄入量将患者分为缓解组和无效组,比较两组患者在年龄、身高、体重、BMI等之间的差异,分析患者手术前和手术后的血糖变化情况、分析手术前和手术后所需血糖控制药物的使用情况等,搜集相关的数据,改变定量,通过统计学进行分析变量之间的差异,从而分析出胃大部分切除术对2型糖尿病患者血糖的影响。结果:所纳入的45例研究对象中:男34例,女11例,胃癌患者30例,其中缓解组29例,无效组16例;平均年龄为63.2岁(缓解组:61.4岁,无效组:67岁),平均患2型糖尿病年限为7.4年(缓解组:5.5年,无效组:10.7年);其中毕Ⅰ式25例,毕Ⅱ式20例。统计学分析发现:两组患者在性别、年龄、术式、BMI、基础疾病等方面没有显著性关联,但是与缓解组相比,无效组患糖尿病年限更长(5.5y VS.10.7y,P0.05);与术前相比,术后1年缓解组的FBG没有显著变化(7.19mmol/L VS.7.23 mmol/L,P0.05)、2h PBG显著降低(11.29mmol/L VS.8.46mmol/L,P0.05),而无效组的FBG显著升高(7.96mmol/L VS.8.34 mmol/L,P0.05)、2h PBG无显著变化(11.06mmol/L VS.10.48 mmol/L,P0.05),组间比较差异有统计学意义。同时与无效组相比,缓解组还显著降低了胰岛素使用量。结论:胃大部切除术对2型糖尿病患者的血糖具有一定的影响,但是此影响取决于患者的糖尿病年限。
[Abstract]:Objective: to investigate the effect of subtotal gastrectomy on blood glucose in patients with type 2 diabetes mellitus. Methods: the clinical data of 99 patients with diabetes mellitus and partial gastrectomy in affiliated Hospital of Yan'an University from 2009 to 2014 were retrospectively analyzed. After selection, 45 cases were selected and the clinical data were complete and the survival time was relatively long. Patients who had no complications and were willing to cooperate were studied. The patients were divided into remission group and ineffective group according to the blood glucose content after operation and the intake needed to control the blood glucose content. The differences between the two groups in age, height, weight, BMI, etc., were compared. We analyzed the changes of blood glucose before and after operation, analyzed the use of blood sugar control drugs before and after operation, collected the relevant data, changed the quantity, and analyzed the differences between variables by statistics. The effects of subtotal gastrectomy on blood glucose in patients with type 2 diabetes mellitus were analyzed. Results: among the 45 subjects, 34 males and 11 females, 30 patients with gastric cancer, 29 patients in remission group and 16 patients in ineffective group. The mean age was 63.2 years (remission group: 61.4 years old, ineffective group: 67 years), and the average age of type 2 diabetes mellitus was 7.4 years (remission group: 5.5 years, ineffective group: 10.7 years), of which 25 cases were type 鈪，

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