中国淋巴瘤亚型分布:国内多中心性病例10002例分析

发布时间：2017-12-28 13:35

本文关键词：中国淋巴瘤亚型分布:国内多中心性病例10002例分析　出处：《诊断学理论与实践》2012年02期 　论文类型：期刊论文

【摘要】：目的:采用国内多中心性合作,回顾性分析10 002例淋巴瘤病例的临床和病理资料,以探讨我国淋巴瘤流行病学特点。方法:组织全国范围内的合作研究,选择来自24家有代表性的医学机构的10 002例淋巴瘤病例,复习其病理切片和临床资料,并作总结分析。结果:10 002例淋巴瘤患者中,男性6188例,女性3814例,男女比为1.6∶1;中位年龄54岁;活检标本取自结外部位相较淋巴结活检略为多见,结内与结外病变比例为1∶1.2。我国人群最常见的淋巴瘤类型是弥漫性大B细胞淋巴瘤(非特指性)(占所有淋巴瘤的33.27%),滤泡性淋巴瘤较西方人群相对少见,而T细胞及NK细胞淋巴瘤在我国人群相对多见(占所有淋巴瘤的21.38%),霍奇金淋巴瘤占所有淋巴瘤的构成比为8.54%,且最常见的亚型为混合细胞型和结节硬化型。结论:我国淋巴瘤亚型分布有其独特特征。
[Abstract]:Objective: To review the clinical and pathological data of 10002 cases of lymphoma, and to explore the epidemiological characteristics of lymphoma in China. Methods: a nationwide cooperative study was conducted, 10002 cases of lymphoma from 24 representative medical institutions were selected, and their pathological sections and clinical data were reviewed. Results: among 10002 lymphoma patients, 6188 were male and 3814 were female, the ratio of male to female was 1.6: 1, median age was 54 years old, biopsy specimens from external locations were more common than lymph node biopsy, and the ratio of intra nodal and extrinsic lesions was 1: 1.2. The most common type of lymphoma in Chinese population is diffuse large B cell lymphoma (unspecified) (accounting for 33.27% of all lymphoma), follicular lymphoma compared with Western populations is relatively rare, while T cells and NK cell lymphoma in our population is relatively rare (accounting for 21.38% of all lymphoma), Hodgkin lymphoma accounted for all lymphoma ratio is 8.54%, and is the most common subtype of mixed cell type and nodular sclerosis type. Conclusion: the distribution of subtype of lymphoma in China has its unique characteristics.
【作者单位】：复旦大学附属肿瘤医院病理科复旦大学上海医学院肿瘤学系;四川大学华西医学院病理学系华西医院病理科;北京大学医学中心病理学系;首都医科大学附属北京友谊医院病理科;中国淋巴瘤病理研究协作组;
【分类号】：R733.1
【正文快照】： 近年来,国内恶性淋巴瘤的发病率有上升趋势。另一方面,随着研究的逐渐深入,越来越多的淋巴瘤类型或亚型正逐渐为人们所认识[1]。但长期以来,关于我国淋巴瘤类型构成和分布的情况,并没有充分的研究资料和数据。鉴于此,在中国抗癌协会淋巴瘤专业委员会的组织下,J Diagn Concepts

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