急性心肌梗死患者GRACE评分与实验室指标的相关性

发布时间：2018-03-02 17:44

本文选题：急性心肌梗死　切入点：GRACE评分　出处：《临床心血管病杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的:研究急性心肌梗死(AMI)患者GRACE评分与实验室检查指标间的相关性。方法:回顾性分析2014-01-2016-09我院心内科收治的AMI患者186例,其中ST段抬高型心肌梗死(STEMI)125例(STEMI组),非ST段抬高型心肌梗死(NSTEMI)61例(NSTEMI组)。计算患者入院时GRACE评分,并将患者分为低危组、中危组、高危组。收集患者一般资料和实验室指标,分析GRACE评分与实验室指标间的相关性。结果:年龄、性别、饮酒史、红细胞压积、GRACE评分在STEMI组与NSTEMI组间差异有统计学意义(P0.05),根据GRACE评分、红细胞压积、年龄绘制ROC曲线下面积分别为0.626[95%可信区间(CI):0.538~0.713,P0.01]、0.633(95%CI:0.542~0.724,P0.01)、0.665(95%CI:0.578~0.752,P0.01),3者联合起来ROC曲线下面积为0.678(95%CI:0.592~0.763,P0.01)。性别、吸烟、饮酒史、D-二聚体、纤维蛋白原降解产物、红细胞压积、红细胞分布宽度、红细胞平均体积、年龄在GRACE评分低、中、高危组间差异有统计学意义(P0.05),相关性分析显示,D-二聚体、纤维蛋白降解产物、红细胞压积、红细胞分布宽度、红细胞平均体积、血小板压积、血小板平均体积、年龄与GRACE评分的相关性差异有统计学意义(P0.05),多元线性回归显示年龄和纤维蛋白原降解产物与GRACE评分独立相关。结论:STEMI组与NSTEMI组患者年龄、性别、饮酒史、红细胞压积、GRACE评分间有差别,实验室检查指标与GRACE评分间有明显相关性。
[Abstract]:Objective: to study the correlation between GRACE score and laboratory examination in patients with acute myocardial infarction (AMI). Methods: a retrospective analysis of 186 AMI patients admitted to our hospital from 2014-01-2016-09 was performed. Among them, 125 patients with ST-segment elevation myocardial infarction and 61 patients with non-ST-segment elevation myocardial infarction were treated with STEMI group and 61 patients with non-ST-segment elevation myocardial infarction group respectively. The GRACE score was calculated and divided into low risk group, middle risk group and high risk group. Results: age, sex, alcohol consumption history, hematocrit score and Grace score were significantly different between STEMI group and NSTEMI group (P 0.05). According to GRACE score, hematocrit was significantly different between STEMI group and NSTEMI group. The area under the ROC curve drawn by age was 0.626 [95% CI: 0.538 / 0.713 P0.01] 0.633 ~ 95% CI0.542U 0.724 P0.01C = 0.66595% CIW 0.5780.752P0.01P0.01. the area under the ROC curve was 0.67895CI0.592C 0.592U 0.763P0.01. Sex, smoking, drinking history, D- dimer, fibrinogen degradation products, hematocrit, erythrocyte distribution width, The mean volume and age of red blood cells were lower than those of GRACE scores. There were significant differences between high risk groups (P 0.05). Correlation analysis showed that D- dimer, fibrin degradation products, hematocrit, distribution width of red blood cells, mean volume of red blood cells, The correlation between platelet volume, mean platelet volume, age and GRACE score was statistically significant (P 0.05). Multiple linear regression analysis showed that age and fibrinogen degradation products were independent of GRACE score. Drinking history, hematocrit GRACE scores were different, and there was a significant correlation between laboratory examination and GRACE score.
【作者单位】：承德医学院附属医院心血管内科;
【分类号】：R542.2

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