心肌梗死患者急诊经皮冠状动脉介入术后脑钠肽的变化及临床特征

发布时间：2018-03-13 22:21

本文选题：急性心肌梗死　切入点：经皮冠状动脉介入术　出处：《中国现代医学杂志》2017年27期 　论文类型：期刊论文

【摘要】：目的探讨ST抬高型心肌梗死(STEMI)和非ST抬高型心肌梗死(NSTEMI)急诊经皮冠状动脉介入术(PCI)后脑钠肽(BNP)的变化和临床特征。方法选取2015年1月-2015年12月急诊入住该院的首发急性心肌梗死患者126例。根据患者入院心电图变化分为STEMI组72例和NSTEMI组54例,并根据冠脉造影结果,分为1支冠脉病变组、2支冠脉病变组和3支冠脉病变组。选取正常患者20例为对照组,测定患者入院后24 h及术后7 d的BNP水平,比较各组间BNP水平的变化及其临床特征。结果入院后24 h 1支病变组、2支病变组和3支病变组的STEMI组的BNP水平均高于NSTEMI组,差异有统计学意义(P0.05)。术后7 d 1支病变组的STEMI组和NSTEMI组的BNP水平比较差异无统计学意义(P0.05),2支病变组、3支病变组的STEMI组的BNP水平低于NSTEMI组,差异有统计学意义(P0.05)。结论急性心肌梗死患者急诊PCI后BNP水平的变化及相关临床特征,有助于更为准确的判断病情、进行危险分层和评估长期的预后等。
[Abstract]:Objective to investigate the changes and clinical characteristics of brain natriuretic peptide (BNPP) in patients with ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) after percutaneous coronary intervention (PCI). 126 patients with acute myocardial infarction were divided into two groups: STEMI group (n = 72) and NSTEMI group (n = 54). According to the results of coronary angiography, the patients were divided into one coronary artery disease group, two coronary artery lesion group and three coronary artery lesion group. 20 normal patients were selected as the control group. The BNP levels of the patients were measured 24 hours after admission and 7 days after operation. Results 24 hours after admission, the level of BNP in the STEMI group was higher than that in the NSTEMI group, and the BNP level in the STEMI group was higher than that in the NSTEMI group. There was no significant difference in BNP level between the STEMI group and the NSTEMI group on the 7th day after operation. The BNP level in the STEMI group was lower than that in the NSTEMI group. Conclusion the changes of BNP level and related clinical features in patients with acute myocardial infarction after emergency PCI are helpful for more accurate diagnosis, risk stratification and evaluation of long-term prognosis.
【作者单位】：新疆医科大学第一附属医院心脏中心;
【分类号】：R542.22

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