肺尘埃沉着病合并高血压患者血管紧张素转化酶水平研究

发布时间：2018-03-14 20:49

本文选题：肺尘埃沉着病　切入点：高血压　出处：《中国全科医学》2017年20期 　论文类型：期刊论文

【摘要】：目的探讨肺尘埃沉着病是否合并高血压的患者血清血管紧张素转化酶(ACE)水平的差异。方法选取2008—2015年广东省职业病防治院住院治疗的肺尘埃沉着病患者300例为研究对象,根据是否合并高血压,将研究对象分为尘肺合并高血压组(37例)及尘肺组(263例)。抽取患者空腹静脉血,测定ACE水平。结果肺尘埃沉着病患者ACE水平为(124.75±75.45)U/L,高于ACE的参考范围上限(100.00 U/L),差异有统计学意义(t=5.635,P0.05)。其中,ACE升高水平138例(46.0%)。尘肺合并高血压组患者年龄高于尘肺组(P0.05)。两组ACE水平比较,差异无统计学意义(P0.05)。线性回归分析显示,肺尘埃沉着病患者ACE水平与性别、年龄、心率、收缩压、舒张压、肺尘埃沉着病分期、空腹血糖均无相关性(P0.05)。结论肺尘埃沉着病患者ACE水平普遍处于较高水平,是否合并高血压的肺尘埃沉着病患者ACE水平未见差异。
[Abstract]:Objective to explore the difference of serum angiotensin converting enzyme (ACE) levels in patients with pneumoconiosis and hypertension. Methods 300 patients with pneumoconiosis who were hospitalized in Guangdong Occupational Disease Prevention and Control Hospital from 2008 to 2015 were selected as subjects. Subjects were divided into pneumoconiosis and hypertension group (37 cases) and pneumoconiosis group (263 cases). Results the ACE level of Pneumoconiosis patients was 124.75 卤75.45 U / L, which was higher than that of ACE (100.00 U / L), and the difference was statistically significant (P < 0.05). Comparison of ACE levels between the two groups, Linear regression analysis showed that ACE levels were correlated with sex, age, heart rate, systolic blood pressure, diastolic blood pressure, pneumoconiosis stage, and age in patients with pneumoconiosis. Conclusion the level of ACE in patients with pneumoconiosis is generally higher than that in patients with hypertension. There is no difference in the level of ACE in patients with Pneumoconiosis complicated with hypertension.
【作者单位】：广东省职业病防治院住院部;
【基金】：国家临床重点专科建设项目
【分类号】：R135.2;R544.1

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