清上温下方治疗上热下寒证高血压的临床研究

发布时间：2018-03-14 22:28

本文选题：高血压　切入点：清上温下方　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过观察清上温下方联合西医抗高血压药物对上热下寒证高血压的降压疗效、中医临床症状的影响,探究清上温下方的临床疗效,为探究清上温下法防治高血压提供依据。方法:采用实用型随机对照试验设计,将入选88例患者随机分为两组:清上温下方联合培哚普利片治疗组(简称治疗组)44例,单纯予培哚普利片治疗组(简称对照组)44例。7天为1个疗程,共5个疗程。记录治疗前后两组患者的中医临床症状积分、诊室血压值及安全性指标。结果:1、诊室血压:治疗组与对照组降压疗效的总有效率分别为93.02%、85.71%,显效率分别为60.47%、40.47%,差异有统计学意义(P0.05);治疗组在收缩压下降幅度方面,明显高于对照组,差异有统计学意义(P0.05);两组治疗后的舒张压比较,差异无统计学意义(P0.05)。2、中医临床症状:治疗组与对照组中医证候疗效的总有效率分别为95.35%、85.72%,显效率分别为65.12%、42.86%,差异有统计学意义(P0.05);治疗组在中医临床症状积分下降幅度方面,明显高于对照组,差异有统计学意义(P0.05)。结论:1、清上温下方联合培哚普利片较单用培哚普利片对上热下寒证高血压患者有更好的降压疗效。2、清上温下方联合培哚普利片可更好地改善中医临床症状。
[Abstract]:Objective: to investigate the clinical effect of Qingshangxia combined with western antihypertensive drugs on hypertension of upper heat and lower cold syndrome and the clinical symptoms of traditional Chinese medicine (TCM). Methods: 88 patients were randomly divided into two groups: 44 cases in the treatment group were treated with Qingshangxia combined with perindopril tablets (abbreviated as the treatment group). The patients in the control group were treated with perindopril alone (control group, 44 cases, 7 days as a course of treatment, 5 courses in total). The clinical symptom scores of the two groups were recorded before and after treatment. Results: the total effective rate of antihypertensive effect in the treatment group and the control group was 93.02 and 85.71, respectively, and the effective rate was 60.47 and 40.47 respectively, the difference was statistically significant (P 0.05). It was significantly higher than that of the control group (P 0.05), and the diastolic blood pressure (DBP) of the two groups was higher than that of the control group (P 0.05). The total effective rate of TCM syndromes in the treatment group and the control group was 95.35 and 85.72, respectively, and the significant effective rate was 65.12 and 42.86 respectively, the difference was statistically significant (P0.05). Significantly higher than the control group, The difference was statistically significant (P 0.05). Conclusion: the combination of perindopril and Qingshangwen is more effective than perindopril alone in lowering blood pressure in patients with hyperthermia and hypothermia, and combined with perindopril tablets can improve the clinical symptoms of traditional Chinese medicine better than that of perindopril in patients with hypertensives with upper heat and lower cold syndrome.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R544.1

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