非左主干真性分叉病变单双支架预后比较

发布时间：2018-04-02 01:09

本文选题：药物洗脱支架　切入点：分叉病变　出处：《皖南医学院》2017年硕士论文

【摘要】：目的:研究非左主干真性分叉病变单双支架的长期预后以及两组间围手术期的差异。方法:共入选98例弋矶山医院的非左主干真性分叉病变的患者,其中79例接受单支架技术治疗,19例接受双支架技术治疗。通过分析两组间围手术期的差异,以及随访两组的主要不良心血管事件(major adverse cardiac event,MACE)、非致命性心肌梗死、靶血管血运重建(target vessel revascularization,TVR)和靶病变血运重建(target lesion revascularization,TLR),评估两种术式长期预后的区别。结果:本研究两组随访了12~116(52.9±30.2)个月,随访期中位数为44.5个月。在单支架亚组中,不同的边支保护方式导致的术中并发症无明显差别。在两组间的边支血管参考直径中,双支架组边支血管参考直径更大,P0.001。两组间的MACE事件发生率无明显差异。两组间的全因死亡、非致命性心肌梗死、TVR也基本相似。结论:不同的边支保护技术对预防术中并发症无明显差异。在非左主干真性分叉病变的治疗中,就长时程随访的全因死亡、TVR、TLR等不良临床结局而言,双支架技术的预后并不优于单支架技术。
[Abstract]:Objective: to study the long term prognosis and the perioperative period difference of single and double stents in non-left main trunk true bifurcation lesions. Methods: 98 patients with non-left main branch true bifurcation lesions were enrolled in this study. Among them, 79 cases were treated with single stent technique and 19 cases received double stent technique. By analyzing the difference of perioperative period between the two groups, the major adverse cardiovascular events of the two groups were followed up, major adverse cardiac events and non-fatal myocardial infarction were followed up. Target vessel revascularization (TVR) and target lesion revascularization (TLR) were used to evaluate the difference of long-term prognosis between the two groups. Results: the two groups were followed up for 12116n 52.9 卤30.2 months, with a median follow-up period of 44.5 months. There was no significant difference in intraoperative complications caused by different collateral protection methods. In the reference diameter of collateral vessels between the two groups, There was no significant difference in the incidence of MACE events between the two groups. There was no significant difference in the incidence of MACE events between the two groups. Conclusion: there is no significant difference in the prevention of intraoperative complications with different collateral protection techniques. The prognosis of double stent technique is not better than that of single stent technique in long term follow-up with TVRV TLR and other adverse clinical outcomes.
【学位授予单位】：皖南医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R541.4

【参考文献】