冠心病左室应变及扭转与临床心功能分级的相关性

发布时间：2018-04-03 19:52

  本文选题：冠心病　切入点：临床心功能　出处：《安徽医科大学学报》2017年01期

【摘要】：目的应用超声斑点追踪技术(STI)检测冠心病(CAD)患者左室应变及扭转参数,并与纽约心功能分级积分(NYHA-P)进行比较分析,探讨STI定量评估CAD心功能分级的价值。方法随机对70例CAD患者按NYHA-P分为纽约心功能分级正常或接近正常组(40例)及心功能分级异常组(30例),并选择正常对照组(30例),比较受检者NYHA-P、左室射血分数(LVEF)、左室心肌整体径向应变(GRS)、纵向应变(GLS)、左室心肌收缩期心肌扭转角度(TA)。结果 CAD组与对照组比较:LVEF、GLS、GRS、TA减低(P0.05);心功能正常组与异常组比较:LVEF、GLS、GRS、TA减低(P0.05);正常组GLS、GRS、TA与LVEF无相关性,与NYHA-P相关;异常组GLS、GRS、TA与LVEF及NYHA-P呈相关性;以GLS-14.65%截断点判定患者NYHAP积分高于4.5分的灵敏度为87.30%、特异度为75%,Yuedden指数最高为0.653。结论 2D-STI技术检测心肌应变及扭转评价CAD左心室局部功能具有独特的优越性,局部应变及扭转参数与左室射血分数不一定相关,但与临床心功能分级相关,应变及扭转评价临床心功能较左室射血分数敏感,可以定量评价CAD患者实际临床心功能状态。
[Abstract]:Objective to detect the parameters of left ventricular strain and torsion in patients with coronary heart disease (CAD) by using ultrasonic dot tracing technique (STI), and to evaluate the value of STI in quantitative evaluation of CAD cardiac function grade.Methods 70 patients with CAD were randomly divided into New York cardiac function grade group (n = 40) and abnormal cardiac function grade group (n = 30) according to NYHA-P, and 30 normal control group (n = 30). The patients were compared with each other (NYHA-P, left ventricular ejection fraction (LVEF), left ventricular ejection fraction (LVEF), left ventricular ejection fraction (LVEF), left ventricular ejection fraction (LVEF)).Global radial strain of myocardium GRSs, longitudinal strain of GLSN, left ventricular torsion angle of myocardial torsion.缁撴灉 CAD缁勪笌瀵圭収缁勬瘮杈，

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