血尿酸水平与主动脉夹层的关系

发布时间：2018-04-03 20:02

  本文选题：主动脉夹层　切入点：尿酸　出处：《新疆医科大学》2015年硕士论文

【摘要】：目的:应用病例对照研究方法探讨血尿酸水平与主动脉夹层的相关性。方法:选取自2012年8月至2014年6月收治的主动脉夹层患者160例为病例组,其中Stanford A型AD组58例,Stanford B型AD组102例,选择同期住院并排除合并AD相关疾病的157例患者为对照组。收集患者的一般资料、既往病史、入院时常规实验室检查,做血尿酸、D-二聚体、超敏CRP水平、血小板计数、白细胞计数、血脂分析、血糖。分析主动脉夹层的相关危险因素。结果:主动脉夹层组和对照组在年龄分布、性别分布、民族分布方面无差异,P0.05,两组在吸烟、饮酒方面相比,差异无统计学意义,P0.05,两组糖尿病、高血压、冠心病分布相比,差异无统计学意义,P0.05。主动脉夹层组血尿酸水平较对照组高,(343.08±136.10mmol/l vs.312.5±85.61mmol/l),P=0.017,Stanford A型AD组血尿酸水平高于Stanford B型AD组,(360.31±47.46mmol/l vs.334.28±48.30mmol/l),P=0.012。经多因素Logistic逐步回归分析显示,高尿酸血症(OR=1.231,95%CI:0.919~0.981)、高血压(OR=1.263,95%CI:1.033~2.099)、CRP(OR=1.526,95%CI:1.094~6.129)、D-二聚体(OR=1.012,95%CI:4.004~5.020)为AD的危险因素。结论:血尿酸水平异常增高与主动脉夹层的发生具有相关性。
[Abstract]:Objective: to investigate the correlation between serum uric acid level and aortic dissection.Methods: one hundred and sixty patients with aortic dissection from August 2012 to June 2014 were selected as the case group, including 58 patients with Stanford A AD and 102 patients with Stanford B AD, and 157 patients who were hospitalized in the same period and excluded from AD related diseases were selected as the control group.General data, past medical history, routine laboratory examination on admission, blood uric acid D-dimer, hypersensitive CRP level, platelet count, white blood cell count, blood lipid analysis, and blood sugar were collected.To analyze the risk factors of aortic dissection.Results: there was no significant difference in age distribution, sex distribution and ethnic distribution between aortic dissection group and control group (P 0.05). There was no significant difference in smoking and drinking between the two groups (P 0.05). The distribution of diabetes, hypertension and coronary heart disease in the two groups was higher than that in the control group.The difference was not statistically significant (P 0.05).涓诲姩鑴夊す灞傜粍琛，

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