无创血流动力学检测评价特发性室性期前收缩患者经导管射频消融术前后心功能变化的临床研究

发布时间：2018-04-08 07:14

本文选题：频发室性期前收缩　切入点：特发性室性早搏　出处：《军事医学》2017年05期

【摘要】：目的联合心脏超声及无创血流动力学检测技术探讨频发室性期前收缩(PVC)患者经导管射频消融术(RFCA)前后心功能变化。方法选取48例特发性频发PVC患者为试验组,PVC总数(16 391.03±10 873.01)个/24 h,另外随机选取55例健康查体者为对照组,分别行心脏超声及无创血流动力学检测。同时选试验组中25例患者行RFCA治疗,于术后3 d行无创血流动力学检测。分别比较两组心脏超声及无创血流动力学检测结果,及RFCA前、后3 d无创血流动力学检测结果。结果所有超声结果均无统计学差异。比较PVC组与对照组的无创血流动力学检测结果,PVC组中心缩力指数(HI)、心搏指数(SI)、心脏指数(CI)、室缩波波幅(C)较对照组降低,差异具有统计学意义(P0.05),而房缩波波幅(WA)、室舒波波幅(O)、左室顺应性指数(WA/C)、舒张功能指数(O/C)较对照组升高,差异具有统计学意义(P0.01);比较RFCA术前与术后3 d患者无创血流动力学检测结果,术后3 d患者HI、SI、CI、C水平显著升高(P0.01),而WA、O、WA/C、O/C较术前降低,差异具有统计学意义。结论特发性PVC患者在病程早期其心功能可能已受损,经RFCA可逆转或防止患者因频发PVC而损及心功能。
[Abstract]:Objective to investigate the changes of cardiac function before and after radiofrequency catheter ablation (RFCA) in patients with frequent ventricular presystolic PVC (PVC) by combination of echocardiography and noninvasive hemodynamic measurement.Methods 48 patients with idiopathic PVC were selected as the experimental group (16 391.03 卤10 873.01) / 24 h, and 55 healthy persons were randomly selected as the control group. The echocardiography and noninvasive hemodynamic examination were performed respectively.At the same time, 25 patients in the trial group were treated with RFCA, and non-invasive hemodynamic examination was performed 3 days after operation.The results of echocardiography and noninvasive hemodynamic examination were compared between the two groups, and the results of noninvasive hemodynamics before and 3 days after RFCA were compared.Results there was no statistical difference in all ultrasound results.The results of noninvasive hemodynamic examination in PVC group and control group were compared. The central contractility index, cardiac systolic index, cardiac index and amplitude of ventricular contraction wave in PVC group were lower than those in control group.The difference was statistically significant (P 0.05), while atrial contraction wave amplitude, ventricular diastolic wave amplitude, left ventricular compliance index, diastolic function index and diastolic function index were higher than those in control group.The difference was statistically significant (P 0.01), and the results of noninvasive hemodynamic examination before and after 3 days of RFCA were compared. The level of CIIC C in patients with RFCA 3 days after operation was significantly higher than that before operation (P 0.01), but it was lower than that before operation, and the difference was statistically significant.Conclusion the cardiac function of idiopathic PVC patients may have been damaged in the early stage of the disease, and RFCA can reverse or prevent the damage of cardiac function due to frequent PVC.
【作者单位】：河北北方学院;空军总医院;
【分类号】：R541.7

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