原发性高血压患者静息心率与迷走神经的关系

发布时间：2018-04-13 05:08

本文选题：原发性高血压 + 静息心率　；参考：《东南大学学报(医学版)》2017年02期

【摘要】：目的:探讨原发性高血压患者静息心率(RHR)与迷走神经张力的关系。方法:404例原发性高血压患者根据GE MAC-800心电图机测定的静息心率分为三组。原发性高血压患者临床资料比较,分别计算迷走神经张力各项指标,比较各组间上述指标差异,并分析各指标与静息心率变化的关系。结果:随着静息心率升高,患者血压水平升高且组间差异显著(P0.05)。静息心率升高显示HF和DC水平均有降低,组间变化明显(P0.05)。除DR4与静息心率呈正相关(r=0.022,P=0.656),HF、DC、DR2及DR8均与静息心率呈负相关(r=-0.428,P=0.000;r=-0.216,P=0.000;r=-0.226,P=0.000;r=-0.040,P=0.422)。回归分析显示,HF、DC、DR4及DR8是静息心率变化的影响因素(P0.05)。ROC曲线分析显示,HF、DC对高血压病具有较好的诊断意义,ROC曲线面积均大于0.8。结论:原发性高血压患者体内迷走神经张力变化引起静息心率升高,其中DRs的三个具有预警病死率能力的参数与静息心率升高有密切联系,静息心率升高可能作为解释原发性高血压患者的病死率的原因之一。
[Abstract]:Objective: to investigate the relationship between resting heart rate (RHR) and vagal nerve tension in patients with essential hypertension.Methods #number0# patients with essential hypertension were divided into three groups according to the resting heart rate measured by GE MAC-800 electrocardiograph.The clinical data of patients with essential hypertension were compared, the indexes of vagal tension were calculated, the differences of the above indexes were compared, and the relationship between the indexes and resting heart rate was analyzed.Results: with the increase of resting heart rate, the level of blood pressure increased and the difference between groups was significant (P 0.05).The increase of resting heart rate showed that both HF and DC levels were decreased, and the changes were significant (P 0.05).In addition, there was a positive correlation between DR4 and resting heart rate. There was a negative correlation between DR8 and resting heart rate. There was a negative correlation between DR8 and resting heart rate.The regression analysis showed that DCDR4 and DR8 were the influencing factors of resting heart rate change. The analysis of P0.05? ROC curve showed that HFC DC had a good diagnostic significance for hypertension and the area of ROC curve was more than 0.8.Conclusion: the changes of vagus nerve tension in patients with essential hypertension cause the increase of resting heart rate. The three parameters of early warning mortality of DRs are closely related to the increase of resting heart rate.Increased resting heart rate may be one of the reasons for the mortality of patients with essential hypertension.
【作者单位】：武汉市第一医院心电诊断科;
【分类号】：R544.1

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