CT对心外膜脂肪体积与升主动脉弹性的相关性

发布时间：2018-04-13 07:16

本文选题：冠心病 + 体层摄影术　；参考：《中国医学影像学杂志》2017年07期

【摘要】：目的运用CT测量结果探讨心外膜脂肪体积与升主动脉弹性的相关性,借以通过心外膜脂肪(EAT)体积早期评估升主动脉病变。资料与方法收集2016年1-9月在锦州医科大学附属第一医院行冠状动脉CT血管造影和冠状动脉造影检查的疑似冠心病患者169例,并根据有无冠状动脉硬化分为对照组(60例)和研究组(109例)。研究组按冠状动脉粥样硬化程度评分分为轻微组、轻度组、中度组和重度组。以文献记载EAT体积的阈值107.2 cm~3为界分为暴露组,其余为非暴露组。测量并计算EAT体积及升主动脉弹性值。分析EAT体积与升主动脉弹性值的相关性以及EAT体积与冠状动脉粥样硬化关系。结果对照组EAT体积与升主动脉弹性值无相关性(r=-0.156,P0.05);轻微、轻度、中度、重度组EAT体积与升主动脉弹性值间均呈负相关(r=-0.378、-0.340、-0.514、-0.459,P0.05);EAT体积是升主动脉弹性值的独立影响因子(β=-0.009,t=-2.653,P0.05);暴露组发生冠心病的风险是非暴露组的9.318倍。结论冠心病患者的EAT体积与升主动脉弹性有明显的相关性。EAT体积的评价能为临床早期预测冠心病患者升主动脉病变的发生提供有效参考。
[Abstract]:Objective to investigate the correlation between epicardial fat volume and ascending aortic elasticity by CT measurement, so as to evaluate ascending aortic lesions early by epicardial fat volume.Materials and methods 169 patients with suspected coronary artery disease who underwent coronary angiography and coronary angiography in the first affiliated Hospital of Jinzhou Medical University from January to September 2016 were collected.The patients were divided into control group (n = 60) and study group (n = 109) according to coronary artery sclerosis.The study group was divided into mild group, mild group, moderate group and severe group according to coronary atherosclerosis score.The threshold of EAT volume of 107.2 cm~3 was divided into exposure group and non-exposed group.The volume of EAT and the elastic value of ascending aorta were measured and calculated.The correlation between EAT volume and ascending aortic elasticity and the relationship between EAT volume and coronary atherosclerosis were analyzed.Results there was no correlation between the volume of EAT and the elasticity of ascending aorta in the control group.There was a negative correlation between the volume of EAT and the elastic value of ascending aorta in severe group. The volume of EAT was an independent factor of ascending aortic elasticity (尾 -0.009) and the risk of coronary heart disease in exposure group was 9.318 times of that in non-exposed group.Conclusion there is a significant correlation between the volume of EAT and the elasticity of ascending aorta in patients with coronary heart disease. The evaluation of ear volume can provide an effective reference for early clinical prediction of ascending aortic disease in patients with coronary heart disease.
【作者单位】：锦州医科大学附属第一医院放射科;唐山市人民医院放射科;
【分类号】：R541.4;R816.2

【参考文献】